Patients with Long-QT Syndrome Caused by Impaired hERG -Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

Louise Hyltén-Cavallius; Eva W Iepsen; Nicolai Jacob Wewer Albrechtsen; Mathilde Svendstrup; Anniek F. Lubberding; Bolette Hartmann; Thomas Jespersen; Allan Linneberg; Michael Christiansen; Henrik Vestergaard; Oluf Pedersen; Jens J. Holst; Jørgen K. Kanters; Torben Hansen; Signe Sørensen Torekov

doi:10.1161/CIRCULATIONAHA.116.024279

Patients with Long-QT Syndrome Caused by Impaired hERG -Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

Louise Hyltén-Cavallius, Eva W Iepsen, Nicolai Jacob Wewer Albrechtsen, Mathilde Svendstrup, Anniek F. Lubberding, Bolette Hartmann, Thomas Jespersen, Allan Linneberg, Michael Christiansen, Henrik Vestergaard, Oluf Pedersen, Jens J. Holst, Jørgen K. Kanters, Torben Hansen, Signe Sørensen Torekov

44 Citations (Scopus)

Original language	English
Journal	Circulation (Baltimore)
Volume	135
Issue number	18
Pages (from-to)	1705-1719
Number of pages	15
ISSN	0009-7322
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.116.024279
Publication status	Published - 2 May 2017

Keywords

arrhythmias, cardiac
glucagon
glucagon-like peptide 1 (GLP-1)
glucose
hyperglycemia
hypoglycemia
insulin-secreting cells
long-QT syndrome
potassium channels, voltage-gated

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10.1161/CIRCULATIONAHA.116.024279

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Hyltén-Cavallius, L., Iepsen, E. W., Wewer Albrechtsen, N. J., Svendstrup, M., Lubberding, A. F., Hartmann, B., Jespersen, T., Linneberg, A., Christiansen, M., Vestergaard, H., Pedersen, O., Holst, J. J., Kanters, J. K., Hansen, T., & Torekov, S. S. (2017). Patients with Long-QT Syndrome Caused by Impaired hERG -Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia. Circulation (Baltimore), 135(18), 1705-1719. https://doi.org/10.1161/CIRCULATIONAHA.116.024279

Patients with Long-QT Syndrome Caused by Impaired hERG -Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia. / Hyltén-Cavallius, Louise; Iepsen, Eva W; Wewer Albrechtsen, Nicolai Jacob et al.
In: Circulation (Baltimore), Vol. 135, No. 18, 02.05.2017, p. 1705-1719.

Research output: Contribution to journal › Journal article › Research › peer-review

Hyltén-Cavallius, L, Iepsen, EW, Wewer Albrechtsen, NJ, Svendstrup, M, Lubberding, AF, Hartmann, B, Jespersen, T, Linneberg, A, Christiansen, M, Vestergaard, H, Pedersen, O, Holst, JJ, Kanters, JK, Hansen, T & Torekov, SS 2017, 'Patients with Long-QT Syndrome Caused by Impaired hERG -Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia', Circulation (Baltimore), vol. 135, no. 18, pp. 1705-1719. https://doi.org/10.1161/CIRCULATIONAHA.116.024279

Hyltén-Cavallius L, Iepsen EW, Wewer Albrechtsen NJ, Svendstrup M, Lubberding AF, Hartmann B et al. Patients with Long-QT Syndrome Caused by Impaired hERG -Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia. Circulation (Baltimore). 2017 May 2;135(18):1705-1719. doi: 10.1161/CIRCULATIONAHA.116.024279

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KW - potassium channels, voltage-gated

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Patients with Long-QT Syndrome Caused by Impaired hERG -Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

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