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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Paget's disease of the bone after treatment with Denosumab: a case report

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  1. Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells

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  2. Hyponatremia and metabolic bone disease in patients with epilepsy: A cross-sectional study

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  3. Comparison of bone turnover markers in peripheral blood and bone marrow aspirate

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  4. A specific subtype of osteoclasts secretes factors inducing nodule formation by osteoblasts

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  1. Vitamin D levels and Cancer Incidence in 217.244 individuals from Primary Health Care in Denmark

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  2. Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes

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  3. An evaluation of total 25-hydroxyvitamin D assay standardization: Where are we today?

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  4. Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

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  5. Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors

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Bone affection in Paget's disease is characterized by increased bone turnover localised at one or more sites of the skeleton. Bisphosphonates are the drugs of choice when treating the increased bone turnover in Paget's disease. However, in cases of decreased kidney function only less effective treatments that are available as bisphosphonates are contraindicated in these patients. We present a case of a male patient aged 86 years with GFR of 11 mL/min and Paget's disease successfully treated by Denosumab. The bone turnover and pain decreased upon treatment.
Original languageEnglish
JournalThe Bone
Volume50
Issue number5
Pages (from-to)1023-5
Number of pages3
ISSN0914-7047
Publication statusPublished - 2012

    Research areas

  • Alkaline Phosphatase, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Humans, Osteitis Deformans, Pelvic Bones

ID: 36832747