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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Paget's disease of the bone after treatment with Denosumab: a case report

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  1. Decreased markers of bone turnover in children and adolescents with type 1 diabetes

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  2. Bone resorption is unchanged by liraglutide in type 2 diabetes patients: A randomised controlled trial

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes

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  4. Continuous decline in bone mineral density and deterioration of bone microarchitecture 7 years after Roux-en-Y gastric bypass surgery

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Bone affection in Paget's disease is characterized by increased bone turnover localised at one or more sites of the skeleton. Bisphosphonates are the drugs of choice when treating the increased bone turnover in Paget's disease. However, in cases of decreased kidney function only less effective treatments that are available as bisphosphonates are contraindicated in these patients. We present a case of a male patient aged 86 years with GFR of 11 mL/min and Paget's disease successfully treated by Denosumab. The bone turnover and pain decreased upon treatment.
Original languageEnglish
JournalThe Bone
Volume50
Issue number5
Pages (from-to)1023-5
Number of pages3
ISSN0914-7047
Publication statusPublished - 2012

    Research areas

  • Alkaline Phosphatase, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Humans, Osteitis Deformans, Pelvic Bones

ID: 36832747