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Optogenetic control of human neurons in organotypic brain cultures

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Optogenetics is one of the most powerful tools in neuroscience, allowing for selective control of specific neuronal populations in the brain of experimental animals, including mammals. We report, for the first time, the application of optogenetic tools to human brain tissue providing a proof-of-concept for the use of optogenetics in neuromodulation of human cortical and hippocampal neurons as a possible tool to explore network mechanisms and develop future therapeutic strategies.

Original languageEnglish
JournalScientific Reports
Volume6
Pages (from-to)24818
Number of pages5
ISSN2045-2322
DOIs
Publication statusPublished - 2016

ID: 46460042