Optic nerve oxygen tension: the effects of timolol and dorzolamide

Jens Folke Kiilgaard; D B Pedersen; T Eysteinsson; M la Cour; K Bang; P K Jensen; E Stefánsson

Optic nerve oxygen tension: the effects of timolol and dorzolamide

Jens Folke Kiilgaard, D B Pedersen, T Eysteinsson, M la Cour, K Bang, P K Jensen, E Stefánsson

Department of Ophthalmology

12 Citations (Scopus)

Abstract

The authors have previously reported that carbonic anhydrase inhibitors such as acetazolamide and dorzolamide raise optic nerve oxygen tension (ONPO(2)) in pigs. The purpose of the present study was to investigate whether timolol, which belongs to another group of glaucoma drugs called beta blockers, has a similar effect. In addition, the effect of dorzolamide and timolol in combination was studied.

Original language	English
Journal	British Journal of Ophthalmology
Volume	88
Issue number	2
Pages (from-to)	276-9
Number of pages	4
ISSN	0007-1161
Publication status	Published - 2004

Keywords

Adrenergic beta-Antagonists
Animals
Antihypertensive Agents
Blood Pressure
Carbon Dioxide
Carbonic Anhydrase Inhibitors
Drug Interactions
Heart Rate
Intraocular Pressure
Optic Disk
Oxygen
Partial Pressure
Sulfonamides
Swine
Thiophenes
Timolol

Cite this

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title = "Optic nerve oxygen tension: the effects of timolol and dorzolamide",

abstract = "The authors have previously reported that carbonic anhydrase inhibitors such as acetazolamide and dorzolamide raise optic nerve oxygen tension (ONPO(2)) in pigs. The purpose of the present study was to investigate whether timolol, which belongs to another group of glaucoma drugs called beta blockers, has a similar effect. In addition, the effect of dorzolamide and timolol in combination was studied.",

keywords = "Adrenergic beta-Antagonists, Animals, Antihypertensive Agents, Blood Pressure, Carbon Dioxide, Carbonic Anhydrase Inhibitors, Drug Interactions, Heart Rate, Intraocular Pressure, Optic Disk, Oxygen, Partial Pressure, Sulfonamides, Swine, Thiophenes, Timolol",

author = "Kiilgaard, \{Jens Folke\} and Pedersen, \{D B\} and T Eysteinsson and \{la Cour\}, M and K Bang and Jensen, \{P K\} and E Stef{\'a}nsson",

year = "2004",

language = "English",

volume = "88",

pages = "276--9",

journal = "British Journal of Ophthalmology",

issn = "0007-1161",

publisher = "BMJ Publishing Group",

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TY - JOUR

T1 - Optic nerve oxygen tension

T2 - the effects of timolol and dorzolamide

AU - Kiilgaard, Jens Folke

AU - Pedersen, D B

AU - Eysteinsson, T

AU - la Cour, M

AU - Bang, K

AU - Jensen, P K

AU - Stefánsson, E

PY - 2004

Y1 - 2004

N2 - The authors have previously reported that carbonic anhydrase inhibitors such as acetazolamide and dorzolamide raise optic nerve oxygen tension (ONPO(2)) in pigs. The purpose of the present study was to investigate whether timolol, which belongs to another group of glaucoma drugs called beta blockers, has a similar effect. In addition, the effect of dorzolamide and timolol in combination was studied.

AB - The authors have previously reported that carbonic anhydrase inhibitors such as acetazolamide and dorzolamide raise optic nerve oxygen tension (ONPO(2)) in pigs. The purpose of the present study was to investigate whether timolol, which belongs to another group of glaucoma drugs called beta blockers, has a similar effect. In addition, the effect of dorzolamide and timolol in combination was studied.

KW - Adrenergic beta-Antagonists

KW - Animals

KW - Antihypertensive Agents

KW - Blood Pressure

KW - Carbon Dioxide

KW - Carbonic Anhydrase Inhibitors

KW - Drug Interactions

KW - Heart Rate

KW - Intraocular Pressure

KW - Optic Disk

KW - Oxygen

KW - Partial Pressure

KW - Sulfonamides

KW - Swine

KW - Thiophenes

KW - Timolol

UR - https://www.scopus.com/pages/publications/0942279520

M3 - Journal article

C2 - 14736791

SN - 0007-1161

VL - 88

SP - 276

EP - 279

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

IS - 2

ER -

Optic nerve oxygen tension: the effects of timolol and dorzolamide

Abstract

Keywords

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