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Ophthalmic nepafenac use in the Netherlands and Denmark

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Harvard

Margulis, AV, Houben, E, Hallas, J, Overbeek, JA, Pottegård, A, Torp-Pedersen, T, Perez-Gutthann, S & Arana, A 2017, 'Ophthalmic nepafenac use in the Netherlands and Denmark' Acta Ophthalmologica (Online), vol. 95, no. 5, pp. 509-517. https://doi.org/10.1111/aos.13468

APA

Margulis, A. V., Houben, E., Hallas, J., Overbeek, J. A., Pottegård, A., Torp-Pedersen, T., ... Arana, A. (2017). Ophthalmic nepafenac use in the Netherlands and Denmark. Acta Ophthalmologica (Online), 95(5), 509-517. https://doi.org/10.1111/aos.13468

CBE

Margulis AV, Houben E, Hallas J, Overbeek JA, Pottegård A, Torp-Pedersen T, Perez-Gutthann S, Arana A. 2017. Ophthalmic nepafenac use in the Netherlands and Denmark. Acta Ophthalmologica (Online). 95(5):509-517. https://doi.org/10.1111/aos.13468

MLA

Vancouver

Margulis AV, Houben E, Hallas J, Overbeek JA, Pottegård A, Torp-Pedersen T et al. Ophthalmic nepafenac use in the Netherlands and Denmark. Acta Ophthalmologica (Online). 2017;95(5):509-517. https://doi.org/10.1111/aos.13468

Author

Margulis, Andrea V ; Houben, Eline ; Hallas, Jesper ; Overbeek, Jetty A ; Pottegård, Anton ; Torp-Pedersen, Tobias ; Perez-Gutthann, Susana ; Arana, Alejandro. / Ophthalmic nepafenac use in the Netherlands and Denmark. In: Acta Ophthalmologica (Online). 2017 ; Vol. 95, No. 5. pp. 509-517.

Bibtex

@article{46e3eebfae7b44a9a7d0bcd4d0753c28,
title = "Ophthalmic nepafenac use in the Netherlands and Denmark",
abstract = "PURPOSE: To describe nepafenac use in the Netherlands and Denmark with reference to its approved indications. For context, we also describe the use of ketorolac and diclofenac.METHODS: We identified users in the PHARMO Database Network (the Netherlands, 2008-2013) and the Danish national health registers (Denmark, 1994-2014). We described prevalence of cataract surgery and duration of use in patients with cataract surgery with and without diabetes.RESULTS: In the Netherlands, 9530 nepafenac users (mean age, 71 years; 60{\%} women) contributed 12 691 therapy episodes, of which 21{\%} had a recently recorded cataract surgery. Of 2266 episodes in adult non-diabetic patients with cataract surgery, 60{\%} had one bottle dispensed (treatment duration ≤21 days). Of 441 episodes in adult diabetic patients with cataract surgery, 90{\%} had up to two bottles dispensed (≤60 days). Denmark had 60 403 nepafenac users (mean age, 72 years; 58{\%} women) and 73 648 episodes (41{\%} had recorded cataract surgery). Of 26 649 nepafenac episodes in adult non-diabetic patients with cataract surgery, 92{\%} had one bottle dispensed. Of 3801 episodes in adult diabetic patients with cataract surgery, 99.8{\%} had up to two bottles dispensed. Use patterns of nepafenac, ketorolac and diclofenac were roughly similar in the Netherlands, but not in Denmark.CONCLUSION: Less than half of therapy episodes were related to cataract surgery; around 90{\%} of episodes with surgery were within the approved duration. Underrecording of ophthalmic conditions and procedures was a challenge in this study.",
keywords = "Aged, Anti-Inflammatory Agents, Non-Steroidal, Benzeneacetamides, Cataract Extraction, Denmark, Drug Utilization, Female, Follow-Up Studies, Humans, Incidence, Male, Netherlands, Ophthalmic Solutions, Phenylacetates, Postoperative Complications, Retrospective Studies, Journal Article, Multicenter Study, Observational Study",
author = "Margulis, {Andrea V} and Eline Houben and Jesper Hallas and Overbeek, {Jetty A} and Anton Potteg{\aa}rd and Tobias Torp-Pedersen and Susana Perez-Gutthann and Alejandro Arana",
note = "{\circledC} 2017 The Authors Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation.",
year = "2017",
doi = "10.1111/aos.13468",
language = "English",
volume = "95",
pages = "509--517",
journal = "Acta Ophthalmologica (Online)",
issn = "1755-3768",
publisher = "Wiley-Blackwell Publishing, Inc",
number = "5",

}

RIS

TY - JOUR

T1 - Ophthalmic nepafenac use in the Netherlands and Denmark

AU - Margulis, Andrea V

AU - Houben, Eline

AU - Hallas, Jesper

AU - Overbeek, Jetty A

AU - Pottegård, Anton

AU - Torp-Pedersen, Tobias

AU - Perez-Gutthann, Susana

AU - Arana, Alejandro

N1 - © 2017 The Authors Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation.

PY - 2017

Y1 - 2017

N2 - PURPOSE: To describe nepafenac use in the Netherlands and Denmark with reference to its approved indications. For context, we also describe the use of ketorolac and diclofenac.METHODS: We identified users in the PHARMO Database Network (the Netherlands, 2008-2013) and the Danish national health registers (Denmark, 1994-2014). We described prevalence of cataract surgery and duration of use in patients with cataract surgery with and without diabetes.RESULTS: In the Netherlands, 9530 nepafenac users (mean age, 71 years; 60% women) contributed 12 691 therapy episodes, of which 21% had a recently recorded cataract surgery. Of 2266 episodes in adult non-diabetic patients with cataract surgery, 60% had one bottle dispensed (treatment duration ≤21 days). Of 441 episodes in adult diabetic patients with cataract surgery, 90% had up to two bottles dispensed (≤60 days). Denmark had 60 403 nepafenac users (mean age, 72 years; 58% women) and 73 648 episodes (41% had recorded cataract surgery). Of 26 649 nepafenac episodes in adult non-diabetic patients with cataract surgery, 92% had one bottle dispensed. Of 3801 episodes in adult diabetic patients with cataract surgery, 99.8% had up to two bottles dispensed. Use patterns of nepafenac, ketorolac and diclofenac were roughly similar in the Netherlands, but not in Denmark.CONCLUSION: Less than half of therapy episodes were related to cataract surgery; around 90% of episodes with surgery were within the approved duration. Underrecording of ophthalmic conditions and procedures was a challenge in this study.

AB - PURPOSE: To describe nepafenac use in the Netherlands and Denmark with reference to its approved indications. For context, we also describe the use of ketorolac and diclofenac.METHODS: We identified users in the PHARMO Database Network (the Netherlands, 2008-2013) and the Danish national health registers (Denmark, 1994-2014). We described prevalence of cataract surgery and duration of use in patients with cataract surgery with and without diabetes.RESULTS: In the Netherlands, 9530 nepafenac users (mean age, 71 years; 60% women) contributed 12 691 therapy episodes, of which 21% had a recently recorded cataract surgery. Of 2266 episodes in adult non-diabetic patients with cataract surgery, 60% had one bottle dispensed (treatment duration ≤21 days). Of 441 episodes in adult diabetic patients with cataract surgery, 90% had up to two bottles dispensed (≤60 days). Denmark had 60 403 nepafenac users (mean age, 72 years; 58% women) and 73 648 episodes (41% had recorded cataract surgery). Of 26 649 nepafenac episodes in adult non-diabetic patients with cataract surgery, 92% had one bottle dispensed. Of 3801 episodes in adult diabetic patients with cataract surgery, 99.8% had up to two bottles dispensed. Use patterns of nepafenac, ketorolac and diclofenac were roughly similar in the Netherlands, but not in Denmark.CONCLUSION: Less than half of therapy episodes were related to cataract surgery; around 90% of episodes with surgery were within the approved duration. Underrecording of ophthalmic conditions and procedures was a challenge in this study.

KW - Aged

KW - Anti-Inflammatory Agents, Non-Steroidal

KW - Benzeneacetamides

KW - Cataract Extraction

KW - Denmark

KW - Drug Utilization

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Incidence

KW - Male

KW - Netherlands

KW - Ophthalmic Solutions

KW - Phenylacetates

KW - Postoperative Complications

KW - Retrospective Studies

KW - Journal Article

KW - Multicenter Study

KW - Observational Study

U2 - 10.1111/aos.13468

DO - 10.1111/aos.13468

M3 - Journal article

VL - 95

SP - 509

EP - 517

JO - Acta Ophthalmologica (Online)

JF - Acta Ophthalmologica (Online)

SN - 1755-3768

IS - 5

ER -

ID: 52799235