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One-week postoperative patency of lower extremity in situ bypass graft comparing epidural and general anesthesia: retrospective study of 822 patients

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BACKGROUND: The purpose of this study was to determine whether anesthesia affects graft patency after lower extremity arterial in situ bypass surgery.

METHODS: This investigation was a retrospective study using a national database on vascular surgical patients at a single medical institution. We assessed a total of 822 patients exposed to infrainguinal in situ bypass vascular surgery over the period of January 2000 to September 2010.

RESULTS: All patients included in the study (age [mean ± SD] 70.8 ± 9.7 years) underwent infrainguinal in situ bypass (n = 885) for lower extremity revascularization under epidural (n = 386) or general (n = 499) anesthesia. Thirty-day mortality (3.4% for epidural anesthesia versus 4.4% general anesthesia; P = 0.414) and comorbidity were comparable in the 2 groups. Graft occlusion within 7 days after surgery was reported in 93 patients, with a similar incidence in the epidural (10.1%) and general (10.8%) anesthesia groups (P = 0.730). When examining a subgroup of patients (n = 242) exposed to surgery on smaller vessels (femorodistal in situ bypass procedures, n = 253), the incidence of graft occlusion was also similar in the 2 groups at 14.0% and 9.4%, respectively (P = 0.262).

CONCLUSION: This retrospective study has shown that when graft patency is evaluated 7 days after surgery, anesthetic choice (epidural or general anesthesia) does not influence outcome.

Original languageEnglish
JournalAnnals of Vascular Surgery
Issue number2
Pages (from-to)295-300
Number of pages6
Publication statusPublished - Feb 2014

    Research areas

  • Aged, Aged, 80 and over, Amputation, Anesthesia, Epidural, Anesthesia, General, Comorbidity, Female, Graft Occlusion, Vascular, Humans, Limb Salvage, Lower Extremity, Male, Middle Aged, Peripheral Arterial Disease, Registries, Reoperation, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, Vascular Patency, Vascular Surgical Procedures

ID: 45092526