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TY - JOUR
T1 - Off-pump versus on-pump coronary artery bypass grafting
AU - Møller, Christian H
AU - Steinbrüchel, Daniel A
PY - 2014/3
Y1 - 2014/3
N2 - Coronary artery bypass grafting (CABG) remains the preferred treatment in patients with complex coronary artery disease. However, whether the procedure should be performed with or without the use of cardiopulmonary bypass, referred to as off-pump and on-pump CABG, is still up for debate. Intuitively, avoidance of cardiopulmonary bypass seems beneficial as the systemic inflammatory response from extracorporeal circulation is omitted, but no single randomized trial has been able to prove off-pump CABG superior to on-pump CABG as regards the hard outcomes death, stroke or myocardial infarction. In contrast, off-pump CABG is technically more challenging and may be associated with increased risk of incomplete revascularization. The purpose of the review is to summarize the current literature comparing outcomes of off-pump versus on-pump coronary artery bypass surgery.
AB - Coronary artery bypass grafting (CABG) remains the preferred treatment in patients with complex coronary artery disease. However, whether the procedure should be performed with or without the use of cardiopulmonary bypass, referred to as off-pump and on-pump CABG, is still up for debate. Intuitively, avoidance of cardiopulmonary bypass seems beneficial as the systemic inflammatory response from extracorporeal circulation is omitted, but no single randomized trial has been able to prove off-pump CABG superior to on-pump CABG as regards the hard outcomes death, stroke or myocardial infarction. In contrast, off-pump CABG is technically more challenging and may be associated with increased risk of incomplete revascularization. The purpose of the review is to summarize the current literature comparing outcomes of off-pump versus on-pump coronary artery bypass surgery.
KW - Acute Kidney Injury
KW - Coronary Artery Bypass
KW - Coronary Artery Bypass, Off-Pump
KW - Coronary Artery Disease
KW - Graft Occlusion, Vascular
KW - Humans
KW - Myocardial Infarction
KW - Risk Factors
KW - Stroke
KW - Treatment Outcome
KW - Vascular Patency
U2 - 10.1007/s11886-013-0455-2
DO - 10.1007/s11886-013-0455-2
M3 - Journal article
VL - 16
SP - 455
JO - Current Cardiology Reports
JF - Current Cardiology Reports
SN - 1534-3170
IS - 3
ER -
ID: 45071598