Observer bias in randomised clinical trials with binary outcomes: systematic review of trials with both blinded and non-blinded outcome assessors

Asbjørn Hróbjartsson; Ann Sofia Skou Thomsen; Frida Emanuelsson; Britta Tendal; Jørgen Hilden; Isabelle Boutron; Philippe Ravaud; Stig Brorson

Observer bias in randomised clinical trials with binary outcomes: systematic review of trials with both blinded and non-blinded outcome assessors

Asbjørn Hróbjartsson, Ann Sofia Skou Thomsen, Frida Emanuelsson, Britta Tendal, Jørgen Hilden, Isabelle Boutron, Philippe Ravaud, Stig Brorson

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Abstract

To evaluate the impact of non-blinded outcome assessment on estimated treatment effects in randomised clinical trials with binary outcomes.

Original language	English
Journal	B M J
Volume	344
Pages (from-to)	e1119
ISSN	0959-8146
Publication status	Published - 2012

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http://www.bmj.com/content/344/bmj.e1119?view=long&pmid=22371859

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title = "Observer bias in randomised clinical trials with binary outcomes: systematic review of trials with both blinded and non-blinded outcome assessors",

abstract = "To evaluate the impact of non-blinded outcome assessment on estimated treatment effects in randomised clinical trials with binary outcomes.",

author = "Asbj{\o}rn Hr{\'o}bjartsson and Thomsen, {Ann Sofia Skou} and Frida Emanuelsson and Britta Tendal and J{\o}rgen Hilden and Isabelle Boutron and Philippe Ravaud and Stig Brorson",

year = "2012",

language = "English",

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journal = "B M J",

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T1 - Observer bias in randomised clinical trials with binary outcomes

T2 - systematic review of trials with both blinded and non-blinded outcome assessors

AU - Hróbjartsson, Asbjørn

AU - Thomsen, Ann Sofia Skou

AU - Emanuelsson, Frida

AU - Tendal, Britta

AU - Hilden, Jørgen

AU - Boutron, Isabelle

AU - Ravaud, Philippe

AU - Brorson, Stig

PY - 2012

Y1 - 2012

N2 - To evaluate the impact of non-blinded outcome assessment on estimated treatment effects in randomised clinical trials with binary outcomes.

AB - To evaluate the impact of non-blinded outcome assessment on estimated treatment effects in randomised clinical trials with binary outcomes.

M3 - Journal article

C2 - 22371859

SN - 0959-8146

VL - 344

SP - e1119

JO - B M J

JF - B M J

ER -

Observer bias in randomised clinical trials with binary outcomes: systematic review of trials with both blinded and non-blinded outcome assessors

Abstract

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