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Nye hormoner relateret til calcium- og fosfathomøostasen ved nyresygdom

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@article{dc765f75b2f242a7bec08501084f2a8b,
title = "Nye hormoner relateret til calcium- og fosfathom{\o}ostasen ved nyresygdom",
abstract = "Calcium and phosphate levels are regulated by a complex interplay between parathyroid hormone (PTH), calcitriol, fibroblast growth factor 23 (FGF23) and its co-receptor αKlotho. Kidney failure causes severe disturbances in the mineral and bone homeostasis resulting in phosphate retention, hypocalcaemia and high plasma levels of FGF23 and PTH, and the patients develop fragile bones and vascular calcifications. Today's treatments aim to lower the levels of phosphate and PTH. Future studies need to clarify, if lowering the FGF23 level or supplementation with αKlotho will improve survival for patients with chronic kidney disease.",
author = "Mace, {Maria Lerche} and Klaus {\O}lgaard and Eva Lewin",
year = "2018",
month = "5",
day = "21",
language = "Dansk",
volume = "180",
pages = "V05170353",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "21",

}

RIS

TY - JOUR

T1 - Nye hormoner relateret til calcium- og fosfathomøostasen ved nyresygdom

AU - Mace, Maria Lerche

AU - Ølgaard, Klaus

AU - Lewin, Eva

PY - 2018/5/21

Y1 - 2018/5/21

N2 - Calcium and phosphate levels are regulated by a complex interplay between parathyroid hormone (PTH), calcitriol, fibroblast growth factor 23 (FGF23) and its co-receptor αKlotho. Kidney failure causes severe disturbances in the mineral and bone homeostasis resulting in phosphate retention, hypocalcaemia and high plasma levels of FGF23 and PTH, and the patients develop fragile bones and vascular calcifications. Today's treatments aim to lower the levels of phosphate and PTH. Future studies need to clarify, if lowering the FGF23 level or supplementation with αKlotho will improve survival for patients with chronic kidney disease.

AB - Calcium and phosphate levels are regulated by a complex interplay between parathyroid hormone (PTH), calcitriol, fibroblast growth factor 23 (FGF23) and its co-receptor αKlotho. Kidney failure causes severe disturbances in the mineral and bone homeostasis resulting in phosphate retention, hypocalcaemia and high plasma levels of FGF23 and PTH, and the patients develop fragile bones and vascular calcifications. Today's treatments aim to lower the levels of phosphate and PTH. Future studies need to clarify, if lowering the FGF23 level or supplementation with αKlotho will improve survival for patients with chronic kidney disease.

M3 - Tidsskriftartikel

VL - 180

SP - V05170353

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 21

ER -

ID: 55810927