Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus

Katarzyna Cypryk; Tina Vilsbøll; Iwona Nadel; Joanna Smyczyńska; Jens Juul Holst; Andrzej Lewiński

Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus

Katarzyna Cypryk, Tina Vilsbøll, Iwona Nadel, Joanna Smyczyńska, Jens Juul Holst, Andrzej Lewiński

30 Citations (Scopus)

Abstract

Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (DM2) are suggested to be caused by the same metabolic disorder. Defects in gut hormone-dependent regulation of beta-cell function (entero-insular axis) have been proposed to contribute to the pathogenesis of DM2. The aim of study was to evaluate whether an impaired secretion of glucagon-like peptide-1 (GLP-1) and/or glucose-dependent insulinotropic polypeptide (GIP) could play a role in the development of carbohydrate disorders during pregnancy.

Original language	English
Journal	Gynecological Endocrinology
Volume	23
Issue number	1
Pages (from-to)	58-62
Number of pages	5
ISSN	0951-3590
Publication status	Published - 1 Jan 2007

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Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus. / Cypryk, Katarzyna; Vilsbøll, Tina; Nadel, Iwona et al.
In: Gynecological Endocrinology, Vol. 23, No. 1, 01.01.2007, p. 58-62.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Holst, Jens Juul

AU - Lewiński, Andrzej

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AB - Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (DM2) are suggested to be caused by the same metabolic disorder. Defects in gut hormone-dependent regulation of beta-cell function (entero-insular axis) have been proposed to contribute to the pathogenesis of DM2. The aim of study was to evaluate whether an impaired secretion of glucagon-like peptide-1 (GLP-1) and/or glucose-dependent insulinotropic polypeptide (GIP) could play a role in the development of carbohydrate disorders during pregnancy.

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Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus

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