Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity

Sven Per Magnus Ågren; Thomas L Andersen; Line Andersen; Christine Bruun Schiødt; Vikas Surve; Troels T. Andreassen; Juha Risteli; Lennart E Franzén; Jean-Marie Delaissé; Anne-Marie Heegaard; Lars Nannestad Jørgensen

doi:10.1007/s00384-010-1106-3

Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity

Sven Per Magnus Ågren, Thomas L Andersen, Line Andersen, Christine Bruun Schiødt, Vikas Surve, Troels T. Andreassen, Juha Risteli, Lennart E Franzén, Jean-Marie Delaissé, Anne-Marie Heegaard, Lars Nannestad Jørgensen

Digestive Disease Center BFH

24 Citations (Scopus)

Abstract

Increased matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of colorectal anastomotic leakage. Tumor necrosis factor-α (TNF-α) induces MMPs and may influence anastomosis repair.

Original language	English
Journal	International Journal of Colorectal Disease
Volume	26
Issue number	3
Pages (from-to)	329-37
Number of pages	9
ISSN	0179-1958
DOIs	https://doi.org/10.1007/s00384-010-1106-3
Publication status	Published - 1 Mar 2011

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Ågren, S. P. M., Andersen, T. L., Andersen, L., Schiødt, C. B., Surve, V., Andreassen, T. T., Risteli, J., Franzén, L. E., Delaissé, J.-M., Heegaard, A.-M., & Jørgensen, L. N. (2011). Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity. International Journal of Colorectal Disease, 26(3), 329-37. https://doi.org/10.1007/s00384-010-1106-3

Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity. / Ågren, Sven Per Magnus; Andersen, Thomas L; Andersen, Line et al.
In: International Journal of Colorectal Disease, Vol. 26, No. 3, 01.03.2011, p. 329-37.

Research output: Contribution to journal › Journal article › Research › peer-review

Ågren, SPM, Andersen, TL, Andersen, L, Schiødt, CB, Surve, V, Andreassen, TT, Risteli, J, Franzén, LE, Delaissé, J-M, Heegaard, A-M & Jørgensen, LN 2011, 'Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity', International Journal of Colorectal Disease, vol. 26, no. 3, pp. 329-37. https://doi.org/10.1007/s00384-010-1106-3

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AU - Surve, Vikas

AU - Andreassen, Troels T.

AU - Risteli, Juha

AU - Franzén, Lennart E

AU - Delaissé, Jean-Marie

AU - Heegaard, Anne-Marie

AU - Jørgensen, Lars Nannestad

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Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity

Abstract

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