Nonkardiale årsager til troponinforhøjelse

Mette Petersen; Nina Strandkjær; Jonas Henrik Kristensen; Shoaib Afzal; Pia Kamstrup; Claus Kjær Pedersen; Carsten Stengaard; Mads Nybo; Martin Overgaard; Søren Andreas Ladefoged; Kasper Iversen; Rasmus Bo Hasselbalch

Nonkardiale årsager til troponinforhøjelse

Translated title of the contribution: Non-cardiac causes of troponin elevation

Mette Petersen, Nina Strandkjær, Jonas Henrik Kristensen, Shoaib Afzal, Pia Kamstrup, Claus Kjær Pedersen, Carsten Stengaard, Mads Nybo, Martin Overgaard, Søren Andreas Ladefoged, Kasper Iversen, Rasmus Bo Hasselbalch

Abstract

With the increased sensitivity of the newest cardiac troponin assays, the risk of false positive cardiac troponin measurements has also increased. As summarised in this review, there are multiple possible causes of cardiac troponin release including several non-cardiac illnesses, particularly kidney disease. Further, there is a risk of analytical interference in which case repeated measurements with a different assay is a good tool. When there is a discrepancy between troponin measurement and clinical presentation of the patient, the clinician should consider the possibility of analytical interference.

Translated title of the contribution	Non-cardiac causes of troponin elevation
Original language	Danish
Article number	V12220753
Journal	Ugeskrift for Laeger
Volume	185
Issue number	20
ISSN	0041-5782
Publication status	Published - 15 May 2023

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title = "Nonkardiale {\aa}rsager til troponinforh{\o}jelse",

abstract = "With the increased sensitivity of the newest cardiac troponin assays, the risk of false positive cardiac troponin measurements has also increased. As summarised in this review, there are multiple possible causes of cardiac troponin release including several non-cardiac illnesses, particularly kidney disease. Further, there is a risk of analytical interference in which case repeated measurements with a different assay is a good tool. When there is a discrepancy between troponin measurement and clinical presentation of the patient, the clinician should consider the possibility of analytical interference.",

keywords = "Humans, Troponin, Troponin T, Biomarkers",

author = "Mette Petersen and Nina Strandkj{\ae}r and Kristensen, {Jonas Henrik} and Shoaib Afzal and Pia Kamstrup and Pedersen, {Claus Kj{\ae}r} and Carsten Stengaard and Mads Nybo and Martin Overgaard and Ladefoged, {S{\o}ren Andreas} and Kasper Iversen and Hasselbalch, {Rasmus Bo}",

year = "2023",

month = may,

day = "15",

language = "Dansk",

volume = "185",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

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TY - JOUR

T1 - Nonkardiale årsager til troponinforhøjelse

AU - Petersen, Mette

AU - Strandkjær, Nina

AU - Kristensen, Jonas Henrik

AU - Afzal, Shoaib

AU - Kamstrup, Pia

AU - Pedersen, Claus Kjær

AU - Stengaard, Carsten

AU - Nybo, Mads

AU - Overgaard, Martin

AU - Ladefoged, Søren Andreas

AU - Iversen, Kasper

AU - Hasselbalch, Rasmus Bo

PY - 2023/5/15

Y1 - 2023/5/15

N2 - With the increased sensitivity of the newest cardiac troponin assays, the risk of false positive cardiac troponin measurements has also increased. As summarised in this review, there are multiple possible causes of cardiac troponin release including several non-cardiac illnesses, particularly kidney disease. Further, there is a risk of analytical interference in which case repeated measurements with a different assay is a good tool. When there is a discrepancy between troponin measurement and clinical presentation of the patient, the clinician should consider the possibility of analytical interference.

AB - With the increased sensitivity of the newest cardiac troponin assays, the risk of false positive cardiac troponin measurements has also increased. As summarised in this review, there are multiple possible causes of cardiac troponin release including several non-cardiac illnesses, particularly kidney disease. Further, there is a risk of analytical interference in which case repeated measurements with a different assay is a good tool. When there is a discrepancy between troponin measurement and clinical presentation of the patient, the clinician should consider the possibility of analytical interference.

KW - Humans

KW - Troponin

KW - Troponin T

KW - Biomarkers

M3 - Review

C2 - 37264867

SN - 0041-5782

VL - 185

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 20

M1 - V12220753

ER -

Nonkardiale årsager til troponinforhøjelse

Abstract

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