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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Noninvasive MRI thermometry with the proton resonance frequency (PRF) method: in vivo results in human muscle.

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  • J De Poorter
  • C De Wagter
  • Y De Deene
  • C Thomsen
  • F Ståhlberg
  • E Achten
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The noninvasive thermometry method is based on the temperature dependence of the proton resonance frequency (PRF). High-quality temperature images can be obtained from phase information of standard gradient-echo sequences with an accuracy of 0.2 degrees C in phantoms. This work was focused on the in vivo capabilities of this method. An experimental setup was designed that allows a qualitative in vivo verification. The lower-leg muscles of a volunteer were cooled and afterwards reheated with an external water bolus. The temperature of the bolus water varied between 17 degrees C and 37 degrees C. The in vivo temperature images can be used to extract the temperature in muscle tissue. The data in the fat tissue are difficult to interpret because of the predominance of susceptibility effects. The results confirm the method's potential for hyperthermia control.
Udgivelsesdato: 1995-Jan
Original languageEnglish
JournalMagnetic Resonance in Medicine
Volume33
Issue number1
Pages (from-to)74-81
Number of pages7
ISSN0740-3194
Publication statusPublished - 1995

    Research areas

  • Algorithms, Body Temperature, Humans, Hyperthermia, Induced, Magnetic Resonance Imaging, Models, Structural, Monitoring, Physiologic, Muscle, Skeletal

ID: 32501602