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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Non-antibiotic antimicrobial interventions and antimicrobial stewardship in wound care

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Assessment of diabetic foot ulcers based on pictorial material: an interobserver study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. FOREWORD

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. SURGICAL SITE INFECTION: PREVENTION AND MANAGEMENT ACROSS HEALTH-CARE SECTORS

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Uncontrolled gelatin degradation in non-healing chronic wounds

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Wound centres-how do we obtain high quality? The EWMA wound centre endorsement project

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. The zone model: A conceptual model for understanding the microenvironment of chronic wound infection

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Staphylococcus aureus Augments Release of Matrix Metalloproteinase-8 from Human Polymorpho-nuclear Leukocytes

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. The host response to bacterial bone infection involves a local upregulation of several acute phase proteins

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Effect of bacterial biofilm on chronic wound fluid composition

    Research output: Book/ReportPh.D. thesis

  5. An exercise program for people with severe peripheral neuropathy and diabetic foot ulcers - a case series on feasibility and safety

    Research output: Contribution to journalJournal articleResearchpeer-review

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Control of wound infection today relies largely on antibiotics, but the continual emergence of antibiotic-resistant microorganisms threatens a return to the pre-antibiotic era when physicians used antiseptics to prevent and manage infection. Some of those antiseptics are still used today, and others have become available. A diverse variety of non-antibiotic antimicrobial interventions are found on modern formularies. Unlike the mode of action of antibiotics, which affect specific cellular target sites of pathogens, many non-antibiotic antimicrobials affect multiple cellular target sites in a non-specific way. Although this reduces the likelihood of selecting for resistant strains of microorganisms, some have emerged and cross-resistance between antibiotics and antiseptics has been detected. With the prospect of a post-antibiotic era looming, ways to maintain and extend our antimicrobial armamentarium must be found. In this narrative review, current and emerging non-antibiotic antimicrobial strategies will be considered and the need for antimicrobial stewardship in wound care will be explained.

Original languageEnglish
JournalJournal of wound care
Volume27
Issue number6
Pages (from-to)355-377
Number of pages23
ISSN0969-0700
DOIs
Publication statusPublished - 2 Jun 2018

ID: 56255750