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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Non-antibiotic antimicrobial interventions and antimicrobial stewardship in wound care

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  1. Uncontrolled gelatin degradation in non-healing chronic wounds

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Wound centres-how do we obtain high quality? The EWMA wound centre endorsement project

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  3. Use of Oxygen Therapies in Wound Healing: Focus on Topical and Hyperbaric Oxygen Treatment

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  4. Prevalence of skin tears in the extremities among elderly residents at a nursing home in Denmark

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  5. The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

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  1. The effect of needle tenotomy on hammer, mallet and claw toe deformities in patients with diabetes, a retrospective study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Incidence and predictors of recurrent and other new diabetic foot ulcers: a retrospective cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Mortality and complications after treatment of acute diabetic Charcot foot

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The clinical path of the Diabetic Charcot Foot. An exploratory study

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  5. Pseudomonas aeruginosa transcriptome during human infection

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Control of wound infection today relies largely on antibiotics, but the continual emergence of antibiotic-resistant microorganisms threatens a return to the pre-antibiotic era when physicians used antiseptics to prevent and manage infection. Some of those antiseptics are still used today, and others have become available. A diverse variety of non-antibiotic antimicrobial interventions are found on modern formularies. Unlike the mode of action of antibiotics, which affect specific cellular target sites of pathogens, many non-antibiotic antimicrobials affect multiple cellular target sites in a non-specific way. Although this reduces the likelihood of selecting for resistant strains of microorganisms, some have emerged and cross-resistance between antibiotics and antiseptics has been detected. With the prospect of a post-antibiotic era looming, ways to maintain and extend our antimicrobial armamentarium must be found. In this narrative review, current and emerging non-antibiotic antimicrobial strategies will be considered and the need for antimicrobial stewardship in wound care will be explained.

Original languageEnglish
JournalJournal of wound care
Volume27
Issue number6
Pages (from-to)355-377
Number of pages23
ISSN0969-0700
DOIs
Publication statusPublished - 2 Jun 2018

ID: 56255750