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Nodular hidradenoma of the caruncle

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@article{2c37489ed6544bbb841787fe4988f982,
title = "Nodular hidradenoma of the caruncle",
abstract = "An 84-year-old man presented with a tumor of the right caruncle causing epiphora due to insufficient eyelid closure. The tumor was cystic and mucinous in appearance. MRI showed a solitary tumor of the caruncle with no adhesions to neighboring tissue. The mass was removed by carunculectomy. Histopathologic examination revealed a tumor composed of epithelial cells with intervening strands of hyalinized stroma. Solid areas were predominant but a cribriform area could also be distinguished. Periodic acid-Schiff positive, diastase-labile material (glycogen) was detected in many tumor cells. Immunohistochemical staining of the tumor cells demonstrated positive staining with antibodies against CK-CAM 5.2, BER-EP4, p63, and smooth muscle actin-positive cells in some areas. The tumor was diagnosed as a nodular hidradenoma of the caruncle, which has never been reported before and should be included in the diagnoses of caruncular tumors.",
keywords = "Acrospiroma, Aged, 80 and over, Conjunctival Neoplasms, Eyelid Neoplasms, Humans, Magnetic Resonance Imaging, Male, Ophthalmologic Surgical Procedures, Sweat Gland Neoplasms, Tumor Markers, Biological",
author = "Christos Christakopoulos and Prause, {Jan Ulrik} and Steffen Heegaard",
year = "2014",
doi = "10.1097/IOP.0b013e3182937542",
language = "English",
volume = "30",
pages = "e37--9",
journal = "Ophthalmic Plastic and Reconstructive Surgery",
issn = "0740-9303",
publisher = "Lippincott Williams & Wilkins",
number = "2",

}

RIS

TY - JOUR

T1 - Nodular hidradenoma of the caruncle

AU - Christakopoulos, Christos

AU - Prause, Jan Ulrik

AU - Heegaard, Steffen

PY - 2014

Y1 - 2014

N2 - An 84-year-old man presented with a tumor of the right caruncle causing epiphora due to insufficient eyelid closure. The tumor was cystic and mucinous in appearance. MRI showed a solitary tumor of the caruncle with no adhesions to neighboring tissue. The mass was removed by carunculectomy. Histopathologic examination revealed a tumor composed of epithelial cells with intervening strands of hyalinized stroma. Solid areas were predominant but a cribriform area could also be distinguished. Periodic acid-Schiff positive, diastase-labile material (glycogen) was detected in many tumor cells. Immunohistochemical staining of the tumor cells demonstrated positive staining with antibodies against CK-CAM 5.2, BER-EP4, p63, and smooth muscle actin-positive cells in some areas. The tumor was diagnosed as a nodular hidradenoma of the caruncle, which has never been reported before and should be included in the diagnoses of caruncular tumors.

AB - An 84-year-old man presented with a tumor of the right caruncle causing epiphora due to insufficient eyelid closure. The tumor was cystic and mucinous in appearance. MRI showed a solitary tumor of the caruncle with no adhesions to neighboring tissue. The mass was removed by carunculectomy. Histopathologic examination revealed a tumor composed of epithelial cells with intervening strands of hyalinized stroma. Solid areas were predominant but a cribriform area could also be distinguished. Periodic acid-Schiff positive, diastase-labile material (glycogen) was detected in many tumor cells. Immunohistochemical staining of the tumor cells demonstrated positive staining with antibodies against CK-CAM 5.2, BER-EP4, p63, and smooth muscle actin-positive cells in some areas. The tumor was diagnosed as a nodular hidradenoma of the caruncle, which has never been reported before and should be included in the diagnoses of caruncular tumors.

KW - Acrospiroma

KW - Aged, 80 and over

KW - Conjunctival Neoplasms

KW - Eyelid Neoplasms

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Ophthalmologic Surgical Procedures

KW - Sweat Gland Neoplasms

KW - Tumor Markers, Biological

U2 - 10.1097/IOP.0b013e3182937542

DO - 10.1097/IOP.0b013e3182937542

M3 - Journal article

VL - 30

SP - e37-9

JO - Ophthalmic Plastic and Reconstructive Surgery

JF - Ophthalmic Plastic and Reconstructive Surgery

SN - 0740-9303

IS - 2

ER -

ID: 45004455