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Nodular hidradenoma of the caruncle

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An 84-year-old man presented with a tumor of the right caruncle causing epiphora due to insufficient eyelid closure. The tumor was cystic and mucinous in appearance. MRI showed a solitary tumor of the caruncle with no adhesions to neighboring tissue. The mass was removed by carunculectomy. Histopathologic examination revealed a tumor composed of epithelial cells with intervening strands of hyalinized stroma. Solid areas were predominant but a cribriform area could also be distinguished. Periodic acid-Schiff positive, diastase-labile material (glycogen) was detected in many tumor cells. Immunohistochemical staining of the tumor cells demonstrated positive staining with antibodies against CK-CAM 5.2, BER-EP4, p63, and smooth muscle actin-positive cells in some areas. The tumor was diagnosed as a nodular hidradenoma of the caruncle, which has never been reported before and should be included in the diagnoses of caruncular tumors.

Original languageEnglish
JournalOphthalmic Plastic and Reconstructive Surgery
Volume30
Issue number2
Pages (from-to)e37-9
ISSN0740-9303
DOIs
Publication statusPublished - 2014

    Research areas

  • Acrospiroma, Aged, 80 and over, Conjunctival Neoplasms, Eyelid Neoplasms, Humans, Magnetic Resonance Imaging, Male, Ophthalmologic Surgical Procedures, Sweat Gland Neoplasms, Tumor Markers, Biological

ID: 45004455