Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

No effects of functional exercise therapy on walking biomechanics in patients with knee osteoarthritis: exploratory outcome analyses from a randomised trial

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Long-standing groin pain in contact sports: a prospective case-control and MRI study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. 10-year follow-up after standardised treatment for Achilles tendinopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Cardiorespiratory fitness and physical function in children with cancer from diagnosis throughout treatment

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Analgesics use and withdrawal in people with dementia - a register-based Danish study and a systematic review

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Weight-bearing MRI of the Lumbar Spine: Spinal Stenosis and Spondylolisthesis

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Weight-bearing MRI of the Lumbar Spine: Technical Aspects

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

AIM: To assess the effects of a functional and individualised exercise programme on gait biomechanics during walking in people with knee OA.

METHODS: Sixty participants were randomised to 12 weeks of facility-based functional and individualised neuromuscular exercise therapy (ET), 3 sessions per week supervised by trained physical therapists, or a no attention control group (CG). Three-dimensional gait analyses were used, from which a comprehensive list of conventional gait variables were extracted (totally 52 kinematic, kinetic and spatiotemporal variables). According to the protocol, the analyses were based on the 'Per-Protocol' population (defined as participants following the protocol with complete and valid gait analyses). Analysis of covariance adjusting for the level at baseline was used to determine differences between groups (95% CIs) in the changes from baseline at follow-up.

RESULTS: The per-protocol population included 46 participants (24 ET/22 CG). There were no group differences in the analysed gait variables, except for a significant group difference in the second peak knee flexor moment and second peak vertical ground reaction force.

CONCLUSION: While plausible we have limited confidence in the findings due to multiple statistical tests and lack of biomechanical logics. Therefore we conclude that a 12-week supervised individualised neuromuscular exercise programme has no effects on gait biomechanics. Future studies should focus on exercise programmes specifically designed to alter gait patterns, or include other measures of mobility, such as walking on stairs or inclined surfaces.

TRIAL REGISTRATION NUMBER: ClinicalTrials.gov: NCT01545258.

Original languageEnglish
JournalBMJ Open Sport & Exercise Medicine
Volume2
Issue number1
Pages (from-to)e000230
ISSN2055-7647
DOIs
Publication statusPublished - 2016

    Research areas

  • Journal Article

ID: 52010617