Neuroendocrine Tumors of the Fallopian Tube: Report of a Case Series and Review of the Literature

Katherine Grondin, Marianne Lidang, Marie Kamper Bønnelycke, Isabel Alvarado-Cabrero, C Simon Herrington, W Glenn McCluggage

Abstract

Primary neuroendocrine tumors of the fallopian tube are extremely rare with a few reported cases of high-grade neuroendocrine carcinoma and a single report of a carcinoid tumor arising in a teratoma. We report 4 cases of probable primary neuroendocrine tumors of the fallopian tube (2 carcinoid tumors/low-grade neuroendocrine tumors and 2 high-grade neuroendocrine carcinomas) in patients aged 49 to 71. These represent the first reported cases of primary tubal carcinoid tumor unassociated with a teratoma. We review the published literature regarding primary neuroendocrine tumors of the fallopian tube and speculate on the possible histogenesis of these neoplasms.

Original languageEnglish
JournalInternational journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Volume38
Issue number1
Pages (from-to)78-84
Number of pages7
ISSN0277-1691
DOIs
Publication statusPublished - Jan 2019

Keywords

  • Aged
  • Carcinoid Tumor/diagnosis
  • Fallopian Tube Neoplasms/diagnosis
  • Fallopian Tubes/pathology
  • Female
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Neuroendocrine Tumors/diagnosis
  • Teratoma/diagnosis

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