Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Neonatal vitamin D status and myopia in young adult men

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Detection of oedema on optical coherence tomography images using deep learning model trained on noisy clinical data

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Branch retinal vein occlusion precipitated by compression between a major retinal artery and underlying optic disc drusen

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Modelling and prognostication of growth in the number of patients treated for neovascular age-related macular degeneration

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Posterior uveal melanoma incidence and survival by AJCC tumour size in a 70-year nationwide cohort

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Intake of n-3 LCPUFA and trans-fatty acids is unrelated to development in body mass index and body fat among children

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Development and cross-cultural validation of the Goal Content for Weight Maintenance Scale (GCWMS)

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

PURPOSE: The prevalence of myopia is increasing worldwide, and modifiable risk factors are thus important to identify. Season of birth has been associated with later myopia risk. Neonatal vitamin D status is highly dependent on season of birth due to maternal sun exposure late in gestation. We hypothesize that prenatal exposure to low levels of vitamin D can interfere with visual development in term-born infants and that this might contribute to adult visual dysfunction. The aim of this study was thus to compare neonatal vitamin D levels from stored dried blood spots taken shortly after birth among young term-born men with myopia (cases) and random controls with emmetropia.

METHODS: In this case-control study, we analysed neonatal 25(OH)D3 levels of 457 myopic male cases and 1280 emmetropic male controls assessed for myopia at the mandatory Danish conscript examination. Data were analysed using logistic regression analysis and results presented as crude and adjusted for potential confounders namely maternal age, maternal ethnicity, maternal and paternal education and season of birth.

RESULTS: We did not observe a seasonal variation in myopia risk, neither did we observe increased odds of myopia in relation to low neonatal 25(OH)D3 levels.

CONCLUSION: The rapid increase in myopia does not seem related to neonatal vitamin D status.

Original languageEnglish
JournalActa Ophthalmologica
Volume98
Issue number5
Pages (from-to)500-505
Number of pages6
ISSN1755-375X
DOIs
Publication statusPublished - 2020

    Research areas

  • 25(OH)D, gestational exposure, myopia, neonatal vitamin D, pregnancy, season

ID: 62050622