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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Neo-antigen specific memory T-cell responses in healthy individuals

Research output: Contribution to journalJournal articleResearchpeer-review

  1. The metabolic enzyme arginase-2 is a potential target for novel immune modulatory vaccines

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  2. Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

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  3. Immunoprofiles of colorectal cancer from Lynch syndrome

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  4. Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma

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  5. T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients

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  1. Lynch syndrome-associated epithelial ovarian cancer and its immunological profile

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. ABO blood types and sepsis mortality

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  3. Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner

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  4. Vaccination against PD-L1 with IO103 a Novel Immune Modulatory Vaccine in Basal Cell Carcinoma: A phase iia study

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The driver mutations in exon 9 of the calreticulin protein have only been identified in patients with myeloid cancers. We recently demonstrated that healthy individuals display strong and frequent T-cell responses towards this mutation. This memory T-cell response is likely evidence of the elimination of mutated cells in healthy individuals.

Original languageEnglish
Article number1599640
JournalOncoImmunology
Volume8
Issue number7
Pages (from-to)1599640
ISSN2162-4011
DOIs
Publication statusPublished - 3 Jul 2019

    Research areas

  • calreticulin, cancer immunoediting, hematological cancer, memory T-cells, Neoantigens

ID: 57730587