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Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

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@article{34921b6011d846a5afbb9782a91db178,
title = "Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes",
abstract = "The ability of glucagon-like peptide-1 (GLP-1) to enhance beta cell responsiveness to i.v. glucose is impaired in patients with type 2 diabetes mellitus compared with healthy individuals. We investigated whether 4 weeks of near normalisation of blood glucose (BG) improves the potentiation of glucose-stimulated insulin secretion by GLP-1.",
author = "H{\o}jberg, {P V} and Zander, {P{\"a}r-Ola Mikael} and Tina Vilsb{\o}ll and Knop, {F K} and T Krarup and Anders V{\o}lund and Holst, {Jens M{\o}ller} and S Madsbad",
year = "2008",
month = "4",
day = "1",
doi = "10.1007/s00125-008-0943-x",
language = "English",
volume = "51",
pages = "632--40",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

AU - Højberg, P V

AU - Zander, Pär-Ola Mikael

AU - Vilsbøll, Tina

AU - Knop, F K

AU - Krarup, T

AU - Vølund, Anders

AU - Holst, Jens Møller

AU - Madsbad, S

PY - 2008/4/1

Y1 - 2008/4/1

N2 - The ability of glucagon-like peptide-1 (GLP-1) to enhance beta cell responsiveness to i.v. glucose is impaired in patients with type 2 diabetes mellitus compared with healthy individuals. We investigated whether 4 weeks of near normalisation of blood glucose (BG) improves the potentiation of glucose-stimulated insulin secretion by GLP-1.

AB - The ability of glucagon-like peptide-1 (GLP-1) to enhance beta cell responsiveness to i.v. glucose is impaired in patients with type 2 diabetes mellitus compared with healthy individuals. We investigated whether 4 weeks of near normalisation of blood glucose (BG) improves the potentiation of glucose-stimulated insulin secretion by GLP-1.

U2 - 10.1007/s00125-008-0943-x

DO - 10.1007/s00125-008-0943-x

M3 - Journal article

VL - 51

SP - 632

EP - 640

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 4

ER -

ID: 32267487