Natriuretic pro-peptides in idiopathic intracranial hypertension

Maren Cecilie Kloppenbor Skau; Jens Peter Gøtze; Jens F. Rehfeld; Rigmor Højland Jensen

doi:10.1016/j.regpep.2010.05.009

Natriuretic pro-peptides in idiopathic intracranial hypertension

Maren Cecilie Kloppenbor Skau, Jens Peter Gøtze, Jens F. Rehfeld, Rigmor Højland Jensen

14 Citations (Scopus)

Abstract

Idiopathic intracranial hypertension is a disorder of unknown pathogenesis. Natriuretic peptides may be involved in intracranial pressure regulation, but cerebrospinal fluid (CNS) and plasma concentrations in this disorder are unknown. We evaluated venous and intrathecal concentrations of ANP, BNP and CNP precursor peptides in 40 patients with idiopathic intracranial hypertension and in 20 controls. Natriuretic pro-peptides were quantitated using processing-independent assays. In CSF, no differences in peptide concentrations between patients and controls were found (proANP: 239 + or - 23 vs 231 + or - 22 pmol/L, proBNP:

Original language	English
Journal	Regulatory Peptides
Volume	164
Issue number	2-3
Pages (from-to)	71-7
Number of pages	7
ISSN	0167-0115
DOIs	https://doi.org/10.1016/j.regpep.2010.05.009
Publication status	Published - 24 Sept 2010

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10.1016/j.regpep.2010.05.009

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AU - Skau, Maren Cecilie Kloppenbor

AU - Gøtze, Jens Peter

AU - Rehfeld, Jens F.

AU - Jensen, Rigmor Højland

PY - 2010/9/24

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N2 - Idiopathic intracranial hypertension is a disorder of unknown pathogenesis. Natriuretic peptides may be involved in intracranial pressure regulation, but cerebrospinal fluid (CNS) and plasma concentrations in this disorder are unknown. We evaluated venous and intrathecal concentrations of ANP, BNP and CNP precursor peptides in 40 patients with idiopathic intracranial hypertension and in 20 controls. Natriuretic pro-peptides were quantitated using processing-independent assays. In CSF, no differences in peptide concentrations between patients and controls were found (proANP: 239 + or - 23 vs 231 + or - 22 pmol/L, proBNP:

AB - Idiopathic intracranial hypertension is a disorder of unknown pathogenesis. Natriuretic peptides may be involved in intracranial pressure regulation, but cerebrospinal fluid (CNS) and plasma concentrations in this disorder are unknown. We evaluated venous and intrathecal concentrations of ANP, BNP and CNP precursor peptides in 40 patients with idiopathic intracranial hypertension and in 20 controls. Natriuretic pro-peptides were quantitated using processing-independent assays. In CSF, no differences in peptide concentrations between patients and controls were found (proANP: 239 + or - 23 vs 231 + or - 22 pmol/L, proBNP:

UR - https://www.scopus.com/pages/publications/77955844905

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DO - 10.1016/j.regpep.2010.05.009

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VL - 164

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JO - Regulatory Peptides

JF - Regulatory Peptides

IS - 2-3

ER -

Natriuretic pro-peptides in idiopathic intracranial hypertension

Abstract

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