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Nationwide trends in the prescription of beta-blockers and angiotensin-converting enzyme inhibitors after myocardial infarction in Denmark, 1995-2002

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@article{146c4627844c40c38376394be0d7b366,
title = "Nationwide trends in the prescription of beta-blockers and angiotensin-converting enzyme inhibitors after myocardial infarction in Denmark, 1995-2002",
abstract = "OBJECTIVES: To study the use of beta-blockers and angiotensin-converting enzyme (ACE) inhibitors after acute myocardial infarction (AMI) in Denmark from 1995 to 2002.DESIGN: Information about patients with first AMI aged > or = 30 years and the dispensing of beta-blockers and ACE inhibitors from pharmacies within 30 d from discharge was obtained from the National Patient Registry and the Danish Registry of Medicinal Product Statistics.RESULTS: Beta-blocker use increased from 38.1% of patients in 1995 to 67.9% in 2002 (OR = 3.85, CI: 3.58-4.13). Women, elderly patients and patients taking loop-diuretics and antidiabetic drugs received beta-blockers less frequently, but patients taking loop-diuretics or antidiabetic drugs had the greatest increase. ACE inhibitor use increased from 24.5 to 35.5% (OR = 1.86, CI: 1.72-2.01). Women, patients aged < 60 years or > or = 80 years and patients not taking loop-diuretics received ACE inhibitors less frequently, but patients not taking loop-diuretics had the greatest increase.CONCLUSIONS: Beta-blocker use increased markedly post-AMI from 1995 to 2002, whereas ACE inhibitor use increased modestly. The results suggested undertreatment of women, elderly patients and people with diabetes.",
keywords = "Adrenergic beta-Antagonists, Age Factors, Angiotensin-Converting Enzyme Inhibitors, Confidence Intervals, Coronary Angiography, Coronary Restenosis, Denmark, Drug Utilization, Female, Follow-Up Studies, Health Care Surveys, Humans, Incidence, Male, Myocardial Infarction, Odds Ratio, Practice Patterns, Physicians', Probability, Registries, Sensitivity and Specificity, Severity of Illness Index, Sex Factors, Survival Rate, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't",
author = "Gislason, {Gunnar H} and Abildstrom, {Steen Z} and Rasmussen, {Jeppe N} and S{\o}ren Rasmussen and Pernille Buch and Ida Gustafsson and Jens Friberg and Niels Gadsb{\o}ll and Lars K{\o}ber and Steen Stender and Mette Madsen and Christian Torp-Pedersen",
year = "2005",
month = apr,
language = "English",
volume = "39",
pages = "42--9",
journal = "Scandinavian Cardiovascular Journal",
issn = "1401-7431",
publisher = "Informa Healthcare",
number = "1-2",

}

RIS

TY - JOUR

T1 - Nationwide trends in the prescription of beta-blockers and angiotensin-converting enzyme inhibitors after myocardial infarction in Denmark, 1995-2002

AU - Gislason, Gunnar H

AU - Abildstrom, Steen Z

AU - Rasmussen, Jeppe N

AU - Rasmussen, Søren

AU - Buch, Pernille

AU - Gustafsson, Ida

AU - Friberg, Jens

AU - Gadsbøll, Niels

AU - Køber, Lars

AU - Stender, Steen

AU - Madsen, Mette

AU - Torp-Pedersen, Christian

PY - 2005/4

Y1 - 2005/4

N2 - OBJECTIVES: To study the use of beta-blockers and angiotensin-converting enzyme (ACE) inhibitors after acute myocardial infarction (AMI) in Denmark from 1995 to 2002.DESIGN: Information about patients with first AMI aged > or = 30 years and the dispensing of beta-blockers and ACE inhibitors from pharmacies within 30 d from discharge was obtained from the National Patient Registry and the Danish Registry of Medicinal Product Statistics.RESULTS: Beta-blocker use increased from 38.1% of patients in 1995 to 67.9% in 2002 (OR = 3.85, CI: 3.58-4.13). Women, elderly patients and patients taking loop-diuretics and antidiabetic drugs received beta-blockers less frequently, but patients taking loop-diuretics or antidiabetic drugs had the greatest increase. ACE inhibitor use increased from 24.5 to 35.5% (OR = 1.86, CI: 1.72-2.01). Women, patients aged < 60 years or > or = 80 years and patients not taking loop-diuretics received ACE inhibitors less frequently, but patients not taking loop-diuretics had the greatest increase.CONCLUSIONS: Beta-blocker use increased markedly post-AMI from 1995 to 2002, whereas ACE inhibitor use increased modestly. The results suggested undertreatment of women, elderly patients and people with diabetes.

AB - OBJECTIVES: To study the use of beta-blockers and angiotensin-converting enzyme (ACE) inhibitors after acute myocardial infarction (AMI) in Denmark from 1995 to 2002.DESIGN: Information about patients with first AMI aged > or = 30 years and the dispensing of beta-blockers and ACE inhibitors from pharmacies within 30 d from discharge was obtained from the National Patient Registry and the Danish Registry of Medicinal Product Statistics.RESULTS: Beta-blocker use increased from 38.1% of patients in 1995 to 67.9% in 2002 (OR = 3.85, CI: 3.58-4.13). Women, elderly patients and patients taking loop-diuretics and antidiabetic drugs received beta-blockers less frequently, but patients taking loop-diuretics or antidiabetic drugs had the greatest increase. ACE inhibitor use increased from 24.5 to 35.5% (OR = 1.86, CI: 1.72-2.01). Women, patients aged < 60 years or > or = 80 years and patients not taking loop-diuretics received ACE inhibitors less frequently, but patients not taking loop-diuretics had the greatest increase.CONCLUSIONS: Beta-blocker use increased markedly post-AMI from 1995 to 2002, whereas ACE inhibitor use increased modestly. The results suggested undertreatment of women, elderly patients and people with diabetes.

KW - Adrenergic beta-Antagonists

KW - Age Factors

KW - Angiotensin-Converting Enzyme Inhibitors

KW - Confidence Intervals

KW - Coronary Angiography

KW - Coronary Restenosis

KW - Denmark

KW - Drug Utilization

KW - Female

KW - Follow-Up Studies

KW - Health Care Surveys

KW - Humans

KW - Incidence

KW - Male

KW - Myocardial Infarction

KW - Odds Ratio

KW - Practice Patterns, Physicians'

KW - Probability

KW - Registries

KW - Sensitivity and Specificity

KW - Severity of Illness Index

KW - Sex Factors

KW - Survival Rate

KW - Comparative Study

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

M3 - Journal article

C2 - 16097413

VL - 39

SP - 42

EP - 49

JO - Scandinavian Cardiovascular Journal

JF - Scandinavian Cardiovascular Journal

SN - 1401-7431

IS - 1-2

ER -

ID: 49503265