Myeloproliferativ cancer og kronisk inflammatorisk tarmsygdom

Heidi Hesselø; Marie Bak; Trine Boysen; Peter Bytzer; Hans Carl Hasselbalch

Myeloproliferativ cancer og kronisk inflammatorisk tarmsygdom

Translated title of the contribution: Myeloproliferative neoplasms and chronic inflammatory bowel disease

Heidi Hesselø
, Marie Bak
, Trine Boysen
, Peter Bytzer
, Hans Carl Hasselbalch

Gastrounit, Medical Division

Abstract

Studies have suggested a possible association between inflammatory bowel disease (IBD) and the Philadelphia-negative chronic myeloproliferative neoplasms (MPNs). The mechanisms behind this association have not been investigated yet, but in this review, we find it most likely to involve complex interactions between genetic, treatment-related and inflammation- and immune-mediated factors. When patients with IBD present with persistent leukocytosis and/or thrombocytosis, it may reflect concomitant MPN, and early detection and treatment of MPNs may prevent some of the complications related to these diseases.

Translated title of the contribution	Myeloproliferative neoplasms and chronic inflammatory bowel disease
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	182
Issue number	22
ISSN	0041-5782
Publication status	Published - 5 May 2020

Cite this

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title = "Myeloproliferativ cancer og kronisk inflammatorisk tarmsygdom",

abstract = "Studies have suggested a possible association between inflammatory bowel disease (IBD) and the Philadelphia-negative chronic myeloproliferative neoplasms (MPNs). The mechanisms behind this association have not been investigated yet, but in this review, we find it most likely to involve complex interactions between genetic, treatment-related and inflammation- and immune-mediated factors. When patients with IBD present with persistent leukocytosis and/or thrombocytosis, it may reflect concomitant MPN, and early detection and treatment of MPNs may prevent some of the complications related to these diseases.",

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T1 - Myeloproliferativ cancer og kronisk inflammatorisk tarmsygdom

AU - Hesselø, Heidi

AU - Bak, Marie

AU - Boysen, Trine

AU - Bytzer, Peter

AU - Hasselbalch, Hans Carl

PY - 2020/5/5

Y1 - 2020/5/5

N2 - Studies have suggested a possible association between inflammatory bowel disease (IBD) and the Philadelphia-negative chronic myeloproliferative neoplasms (MPNs). The mechanisms behind this association have not been investigated yet, but in this review, we find it most likely to involve complex interactions between genetic, treatment-related and inflammation- and immune-mediated factors. When patients with IBD present with persistent leukocytosis and/or thrombocytosis, it may reflect concomitant MPN, and early detection and treatment of MPNs may prevent some of the complications related to these diseases.

AB - Studies have suggested a possible association between inflammatory bowel disease (IBD) and the Philadelphia-negative chronic myeloproliferative neoplasms (MPNs). The mechanisms behind this association have not been investigated yet, but in this review, we find it most likely to involve complex interactions between genetic, treatment-related and inflammation- and immune-mediated factors. When patients with IBD present with persistent leukocytosis and/or thrombocytosis, it may reflect concomitant MPN, and early detection and treatment of MPNs may prevent some of the complications related to these diseases.

M3 - Tidsskriftartikel

C2 - 32515326

SN - 0041-5782

VL - 182

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 22

ER -

Myeloproliferativ cancer og kronisk inflammatorisk tarmsygdom

Abstract

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