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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Multispectral imaging of hand eczema

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BACKGROUND: Hand eczema is a disease with large variation in clinical presentation and severity. Scoring systems for quantitative severity assessment exist. However, they are observer-dependent. An objective quantitative tool for scoring of hand eczema would improve categorization of hand eczema.

OBJECTIVE: To investigate the usefulness of multispectral imaging in assessing severity of hand eczema with respect to extent and the different morphological features.

METHODS: Patients with hand eczema (n = 60) and healthy controls (n = 28) were included. The severity of hand eczema was assessed by a dermatologist using the Hand Eczema Severity Index (HECSI) and a global assessment (Physician Global Assessment [PGA]). Multispectral imaging of the hand was performed on all patients and controls using the VideometerLab Instrument.

RESULTS: Areas of the morphological elements identified by multispectral imaging were statistically significantly correlated with the PGA scores. Analyzed by Cohen's kappa, a moderate agreement between imaging-based severity assessment and PGA was found. The imaging-based severity assessment was also correlated with HECSI (Spearman rho 0.683, P < .001). Still, the imaging-based algorithm was not capable of differentiating hand eczema patients from controls.

CONCLUSIONS: Multispectral imaging allows quantitative measurements of different skin parameters to be performed. In its present form, multispectral imaging cannot replace the clinical assessment of a dermatologist. However, after refinement, this or similar technologies could prove useful.

Original languageEnglish
JournalContact Dermatitis
Volume81
Issue number6
Pages (from-to)438-445
Number of pages8
ISSN0105-1873
DOIs
Publication statusPublished - Dec 2019

ID: 58983090