Multiparametric flow cytometry profiling of neoplastic plasma cells in multiple myeloma

Hans E Johnsen, Martin Bøgsted, Tobias Wirenfeldt Klausen, Peter Gimsing, Alexander Schmitz, Erik Kjaersgaard, Tina Damgaard, Pia Voss, Lene M Knudsen, Anne K Mylin, Johan Lanng Nielsen, Bo Björkstrand, Astrid Gruber, Stig Lenhoff, Kari Remes, Inger Marie Dahl, Kirsten Fogd, Karen Dybkaer, Nordic Myeloma Study (NMSG)

    28 Citations (Scopus)


    The clinical impact of multiparametric flow cytometry (MFC) in multiple myeloma (MM) is still unclear and under evaluation. Further progress relies on multiparametric profiling of the neoplastic plasma cell (PC) compartment to provide an accurate image of the stage of differentiation. The primary aim of this study was to perform global analysis of CD expression on the PC compartment and subsequently to evaluate the prognostic impact. Secondary aims were to study the diagnostic and predictive impact.
    Original languageEnglish
    JournalCytometry. Part B: Clinical Cytometry
    Issue number5
    Pages (from-to)338-47
    Number of pages10
    Publication statusPublished - 1 Sep 2010


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