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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Multi-modal and multi-scale clinical retinal imaging system with pupil and retinal tracking

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We present a compact multi-modal and multi-scale retinal imaging instrument with an angiographic functional extension for clinical use. The system integrates scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT) and OCT angiography (OCTA) imaging modalities and provides multi-scale fields of view. For high resolution, and high lateral resolution in particular, cellular imaging correction of aberrations by adaptive optics (AO) is employed. The entire instrument has a compact design and the scanning head is mounted on motorized translation stages that enable 3D self-alignment with respect to the subject's eye by tracking the pupil position. Retinal tracking, based on the information provided by SLO, is incorporated in the instrument to compensate for retinal motion during OCT imaging. The imaging capabilities of the multi-modal and multi-scale instrument were tested by imaging healthy volunteers and patients.

Original languageEnglish
Article number9577
JournalScientific Reports
Volume12
Issue number1
Pages (from-to)9577
ISSN2045-2322
DOIs
Publication statusPublished - 10 Jun 2022

Bibliographical note

© 2022. The Author(s).

    Research areas

  • Humans, Ophthalmoscopy/methods, Optics and Photonics, Pupil, Retina/diagnostic imaging, Tomography, Optical Coherence/methods

ID: 78742955