Mortality among patients with cleared hepatitis C virus infection compared to the general population: a Danish nationwide cohort study

Lars Haukali Omland; Peer Brehm Christensen; Henrik Bygum Krarup; Peter Jepsen; Nina Margrethe Weis; Henrik Toft Sørensen; Niels Obel; DANVIR Cohort Study

doi:10.1371/journal.pone.0022476

Mortality among patients with cleared hepatitis C virus infection compared to the general population: a Danish nationwide cohort study

Lars Haukali Omland
, Peer Brehm Christensen
, Henrik Bygum Krarup
, Peter Jepsen
, Nina Margrethe Weis
, Henrik Toft Sørensen
, Niels Obel
, DANVIR Cohort Study

Department of Infectious Diseases

19 Citations (Scopus)

Abstract

The increased mortality in HCV-infected individuals partly stems from viral damage to the liver and partly from risk-taking behaviours. We examined mortality in patients who cleared their HCV-infection, comparing it to that of the general population. We also addressed the question whether prognosis differed according to age, substance abuse (alcohol abuse and injection drug use) and comorbidity.

Original language	English
Journal	P L o S One
Volume	6
Issue number	7
Pages (from-to)	e22476
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0022476
Publication status	Published - Jul 2011

Keywords

Adult
Alcoholism
Cause of Death
Cohort Studies
Comorbidity
Denmark
Female
Hepacivirus
Hepatitis C
Humans
Incidence
Kaplan-Meier Estimate
Male
Middle Aged
Substance Abuse, Intravenous

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10.1371/journal.pone.0022476

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abstract = "The increased mortality in HCV-infected individuals partly stems from viral damage to the liver and partly from risk-taking behaviours. We examined mortality in patients who cleared their HCV-infection, comparing it to that of the general population. We also addressed the question whether prognosis differed according to age, substance abuse (alcohol abuse and injection drug use) and comorbidity.",

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AU - Omland, Lars Haukali

AU - Christensen, Peer Brehm

AU - Krarup, Henrik Bygum

AU - Jepsen, Peter

AU - Weis, Nina Margrethe

AU - Sørensen, Henrik Toft

AU - Obel, Niels

AU - DANVIR Cohort Study

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AB - The increased mortality in HCV-infected individuals partly stems from viral damage to the liver and partly from risk-taking behaviours. We examined mortality in patients who cleared their HCV-infection, comparing it to that of the general population. We also addressed the question whether prognosis differed according to age, substance abuse (alcohol abuse and injection drug use) and comorbidity.

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KW - Alcoholism

KW - Cause of Death

KW - Cohort Studies

KW - Comorbidity

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KW - Female

KW - Hepacivirus

KW - Hepatitis C

KW - Humans

KW - Incidence

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Substance Abuse, Intravenous

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JF - P L o S One

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ER -

Mortality among patients with cleared hepatitis C virus infection compared to the general population: a Danish nationwide cohort study

Abstract

Keywords

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