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Monitoring and treatment of anti-D in pregnancy

D Bettelheim, S Panzer, H W Reesink, B Csapo, C Pessoa, F Guerra, S Wendel, P Calda, U Sprogøe, M Dziegiel, A Aitokallio-Tallberg, S Koskinen, M Kuosmanen, T J Legler, W Stein, S Villa, M A Villa, L Trespidi, B Acaia, F P H A VandenbusscheA Brand, M de Haas, H H H Kanhai, D Gounder, P Flanagan, R Donegan, E Parry, C Sefonte, S M Skulstad, T Hervig, Ø Flesland, B Zupańska, M Uhrynowska, O Lapaire, X Y Zhong, W Holzgreve

8 Citations (Scopus)

Abstract

Prophylactic anti-D is a very safe and effective therapy for the suppression of anti-D immunization and thus prevention of haemolytic disease of the foetus and newborn. However, migration from countries with low health standards and substantial cuts in public health expenses have increased the incidence of anti-D immunization in many "developed" countries. Therefore, this forum focuses on prenatal monitoring standards and treatment strategies in pregnancies with anti-D alloimmunization. The following questions were addressed, and a response was obtained from 12 centres, mainly from Europe.

Original languageEnglish
JournalVox Sanguinis
Volume99
Issue number2
Pages (from-to)177-92
Number of pages16
ISSN0042-9007
DOIs
Publication statusPublished - 1 Aug 2010

Keywords

  • Blood Group Antigens/immunology
  • Female
  • Fetal Blood/immunology
  • Fetal Hemoglobin/analysis
  • Humans
  • Isoantibodies/administration & dosage
  • Pregnancy
  • Pregnancy Complications, Hematologic/blood
  • Rh Isoimmunization/immunology
  • Rh-Hr Blood-Group System/immunology
  • Rho(D) Immune Globulin

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