Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

Henrik Rasmus Maltesen; Claus H Nielsen; Christina Schjellerup Dalbøge; Bo Baslund

doi:10.1093/rheumatology/keq213

Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

Henrik Rasmus Maltesen, Claus H Nielsen, Christina Schjellerup Dalbøge, Bo Baslund

7 Citations (Scopus)

Abstract

Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.

Original language	English
Journal	Rheumatology (Oxford, England)
Volume	49
Issue number	11
Pages (from-to)	2037-42
Number of pages	6
DOIs	https://doi.org/10.1093/rheumatology/keq213
Publication status	Published - 1 Nov 2010

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title = "Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation",

abstract = "Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.",

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T1 - Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

AU - Maltesen, Henrik Rasmus

AU - Nielsen, Claus H

AU - Dalbøge, Christina Schjellerup

AU - Baslund, Bo

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.

AB - Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.

U2 - 10.1093/rheumatology/keq213

DO - 10.1093/rheumatology/keq213

M3 - Journal article

C2 - 20634232

VL - 49

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JO - Rheumatology

JF - Rheumatology

SN - 1462-0324

IS - 11

ER -

Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

Abstract

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