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Methodological issues of postoperative cognitive dysfunction research

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  1. Elevated Renal Oxygen Extraction During Open Abdominal Aortic Aneurysm Repair Is Related to Postoperative Renal Dysfunction

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  2. Symptoms presented during emergency telephone calls for patients with spontaneous subarachnoid haemorrhage

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  3. Hemorrhage and saline resuscitation are associated with epigenetic and proteomic reprogramming in the rat lung

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  4. Supplemental oxygen therapy in trauma patients: an exploratory registry-based study

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Postoperative cognitive dysfunction (POCD) is a subtle impairment of memory, concentration, and speed of information processing. It is a frequent complication following surgery and can have a debilitating effect on patients' recovery and future prognosis. Neuropsychological testing is needed to reveal postoperative cognitive decline, and questionnaires are not useful for this purpose. There is a profound lack of consensus regarding the research methodology for detection of cognitive deterioration, especially the diagnostic criteria. Issues, such as baseline performance, learning effects, and the interval between test sessions, also influence test results and must be considered when designing and interpreting POCD data.
Original languageEnglish
JournalSeminars in Cardiothoracic and Vascular Anesthesia
Volume14
Issue number2
Pages (from-to)119-22
Number of pages4
ISSN1089-2532
DOIs
Publication statusPublished - 1 Jun 2010

ID: 31028592