Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Metabolic Surgery for Hypertension in Patients With Obesity

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes

    Research output: Contribution to journalReviewResearchpeer-review

  3. Genetics of Coronary Artery Disease

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Serum Potassium and Mortality in High-Risk Patients: SPRINT

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Mortality and ventricular arrhythmia after acute myocarditis: a nationwide registry-based follow-up study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Predictive Importance of Blood Pressure Characteristics With Increasing Age in Healthy Men and Women: The MORGAM Project

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Manan Pareek
  • Deepak L Bhatt
  • Carlos Aurelio Schiavon
  • Philip R Schauer
View graph of relations

The global prevalence of overweight and obesity has risen substantially over the past 4 decades and is accompanied by an increasing burden of cardiovascular risk factors such as hypertension. Metabolic surgery is the most effective method to treat obesity and may further improve associated conditions. Although most research has been directed toward the glycemic effects of weight loss surgery, there has been a growing interest in exploring its potential blood pressure-reducing properties. Systematic reviews and meta-analyses based primarily on observational data have suggested that metabolic surgery may aid in controlling hypertension. Only one randomized controlled trial specifically addressing this concept has been conducted, though supportive of the findings from observational studies. We review contemporary procedures for weight loss and their effects on cardiometabolic risk, particularly hypertension. In addition, we describe potential pathophysiological mechanisms and the effects of metabolic surgery on cardiovascular events and mortality.

Original languageEnglish
JournalCirculation Research
Volume124
Issue number7
Pages (from-to)1009-1024
Number of pages16
ISSN0009-7330
DOIs
Publication statusPublished - 2019

    Research areas

  • bariatric surgery, blood pressure, hypertension, obesity, weight loss

ID: 57239270