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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Mesenchymal stromal cell phenotype is not influenced by confluence during culture expansion

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  1. An In Vitro Differentiation Protocol for Human Embryonic Bipotential Gonad and Testis Cell Development

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  2. Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

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  3. Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage

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  1. Impaired coronary flow velocity reserve is associated with cardiovascular risk factors but not with angina symptoms

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  2. Safety and feasibility of mesenchymal stem cell therapy in patients with aqueous deficient dry eye disease

    Research output: Contribution to journalJournal articleResearchpeer-review

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Accumulating preclinical and clinical evidence indicates that human mesenchymal stromal cells (MSCs) are good candidates for cell therapy. For clinical applications of MSCs extensive in vitro expansion is required to obtain an adequate number of cells. It is evident that the pursuit for cell quantity must not affect quality, but it is also a fact that in vitro culture conditions affect MSC phenotype. One possible variable is the degree of cell confluence during expansion.
Original languageEnglish
JournalStem Cell Reviews
Volume9
Issue number1
Pages (from-to)44-58
Number of pages15
ISSN1550-8943
DOIs
Publication statusPublished - Feb 2013

    Research areas

  • Adult, Biological Markers, Bone Marrow Cells, Cell Count, Cell Culture Techniques, Cell Differentiation, Cell Proliferation, Cells, Cultured, Female, Gene Expression, Humans, Male, Mesenchymal Stromal Cells, Phenotype, RNA, Messenger, Young Adult

ID: 42941469