Abstract
OBJECTIVE: The purpose of this study is to examine whether mental vulnerability is a risk factor for the development of ischemic heart disease (IHD) after adjustment for well-established risk factors. METHODS: In three prospective cohort studies in Copenhagen County, Denmark, we recorded the level of mental vulnerability and possible risk factors to IHD at baseline. For follow-up, the sample was linked to relevant registries to identify all cases of fatal and nonfatal IHD. The relationship between mental vulnerability and IHD was examined using both Kaplan-Meir and Cox proportional hazard models adjusting for possible confounding factors. RESULTS: Mental vulnerability was significantly associated with the risk for IHD (medium mental vulnerability: hazard ratio 1.41, 95% confidence interval 1.04-1.91; and high mental vulnerability: hazard ratio 2.05; 95% confidence interval 1.46-2.88), after adjusting for confounders. CONCLUSION: Our results imply that mental vulnerability is an independent risk factor for IHD.
Udgivelsesdato: 2006-Feb
Udgivelsesdato: 2006-Feb
Original language | English |
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Journal | Journal of Psychosomatic Research |
Volume | 60 |
Issue number | 2 |
Pages (from-to) | 169-76 |
Number of pages | 7 |
ISSN | 0022-3999 |
DOIs | |
Publication status | Published - 2006 |
Keywords
- Adult
- Aged
- Cause of Death
- Cohort Studies
- Comorbidity
- Denmark
- Female
- Follow-Up Studies
- Health Surveys
- Humans
- Male
- Middle Aged
- Myocardial Ischemia
- Personality Inventory
- Proportional Hazards Models
- Psychophysiologic Disorders
- Referral and Consultation
- Risk Factors
- Vulnerable Populations