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Meditation and mindfulness reduce perceived stress in women with recurrent pregnancy loss: a randomized controlled trial

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Research question: Can participating in a tailored 7-week meditation and mindfulness programme with additional standard supportive care versus standard supportive care only reduce perceived stress for women with recurrent pregnancy loss (RPL)? Design: A two-armed randomized controlled trial (RCT) with 12-month follow-up. In total 76 patients were enrolled and randomly assigned to either standard supportive care or to a 7-week meditation and mindfulness programme led by an instructor in addition to standard supportive care. Results: At intervention completion (after 7 weeks), perceived stress decreased significantly both in the intervention group (P = 0.001) and in the control group (P = 0.006). The decrease in perceived stress in the intervention group was significantly larger (P = 0.027) compared with the control group. At the 12-month follow-up perceived stress was still significantly decreased in both groups compared with baseline (P < 0.0001 in the intervention group and P = 0.002 in the control group). Conclusion: This first RCT of a tailored meditation and mindfulness intervention for women with RPL documents that a 7-week daily at-home meditation and mindfulness programme combined with group sessions reduced perceived stress significantly more than a standard supportive care programme. Future studies should address the most effective format and the ‘dose’ needed for an impact on perceived stress levels.

Original languageEnglish
JournalReproductive BioMedicine Online
Volume43
Issue number2
Pages (from-to)246-256
Number of pages11
ISSN1472-6483
DOIs
Publication statusPublished - Aug 2021

    Research areas

  • Education, Meditation, Randomized controlled trial, Recurrent pregnancy loss, Stress

ID: 66308249