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Measurement of the arterial concentration of Gd-DTPA using MRI: a step toward quantitative perfusion imaging.

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  1. Quantification of cerebral perfusion and cerebrovascular reserve using Turbo-QUASAR arterial spin labeling MRI

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  2. Coil profile estimation strategies for parallel imaging with hyperpolarized 13 C MRI

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  3. Gamma-aminobutyric acid edited echo-planar spectroscopic imaging (EPSI) with MEGA-sLASER at 7T

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  4. Comparison of prospective head motion correction with NMR field probes and an optical tracking system

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  5. Improved calculation of the equilibrium magnetization of arterial blood in arterial spin labeling

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A noninvasive method using an inversion recovery turbo-FLASH for dynamic measurement of the arterial input function represented by the bolus passage of Gd-DTPA in the descending aorta is presented, and the results are compared with the input function obtained by arterial blood samples. A good accordance between the two input functions was found, indicating that it is possible to measure the input function to the myocardium using MRI. A variation between the two concentration curves of 5% at upslope, 2.7% at peak point, and < 7% at downslope was found. The study also indicates that a short inversion time < 250 ms has to be used to ensure correct measurement of peak concentration.
Translated title of the contributionMeasurement of the arterial concentration of Gd-DTPA using MRI: a step toward quantitative perfusion imaging.
Original languageEnglish
JournalMagnetic Resonance in Medicine
Volume36
Issue number2
Pages (from-to)225-231
Number of pages7
ISSN0740-3194
Publication statusPublished - 1996

ID: 32562835