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Measurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.

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  • H B Larsson
  • P S Tofts
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Two recently published methods of blood-brain barrier permeability measurement using Gd-DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface area product per unit volume of tissue) of the defective blood-brain barrier in multiple sclerosis is in the range 1-12.10(-4) s-1.
Translated title of the contributionMeasurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.
Original languageEnglish
JournalMagnetic Resonance in Medicine
Volume24
Issue number1
Pages (from-to)174-176
Number of pages3
ISSN0740-3194
Publication statusPublished - 1992

ID: 32500288