Measurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.

H B Larsson; P S Tofts

Measurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.

H B Larsson
, P S Tofts

Danish Research Centre for Magnetic Resonance

59 Citations (Scopus)

Abstract

Two recently published methods of blood-brain barrier permeability measurement using Gd-DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface area product per unit volume of tissue) of the defective blood-brain barrier in multiple sclerosis is in the range 1-12.10(-4) s-1.

Translated title of the contribution	Measurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.
Original language	English
Journal	Magnetic Resonance in Medicine
Volume	24
Issue number	1
Pages (from-to)	174-176
Number of pages	3
ISSN	0740-3194
Publication status	Published - 1992

Access to Document

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1556924&query_hl=41

Cite this

@article{80fa92455442498d98bbfe93e2ed3000,

title = "Measurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.",

abstract = "Two recently published methods of blood-brain barrier permeability measurement using Gd-DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface area product per unit volume of tissue) of the defective blood-brain barrier in multiple sclerosis is in the range 1-12.10(-4) s-1.",

author = "Larsson, \{H B\} and Tofts, \{P S\}",

year = "1992",

language = "English",

volume = "24",

pages = "174--176",

journal = "Magnetic Resonance in Medicine",

issn = "0740-3194",

publisher = "John Wiley and Sons Inc.",

number = "1",

}

TY - JOUR

T1 - Measurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.

AU - Larsson, H B

AU - Tofts, P S

PY - 1992

Y1 - 1992

N2 - Two recently published methods of blood-brain barrier permeability measurement using Gd-DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface area product per unit volume of tissue) of the defective blood-brain barrier in multiple sclerosis is in the range 1-12.10(-4) s-1.

AB - Two recently published methods of blood-brain barrier permeability measurement using Gd-DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface area product per unit volume of tissue) of the defective blood-brain barrier in multiple sclerosis is in the range 1-12.10(-4) s-1.

M3 - Journal article

SN - 0740-3194

VL - 24

SP - 174

EP - 176

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

IS - 1

ER -