Many putative endocrine disruptors inhibit prostaglandin synthesis

David M Kristensen, Maria L Skalkam, Karine Marie Laure Audouze, Laurianne Lesné, Christele Desdoits-Lethimonier, Hanne Frederiksen, Søren Brunak, Niels E Skakkebæk, Bernard Jégou, Jacob Busk Hansen, Steffen Junker, Henrik Leffers

80 Citations (Scopus)


Prostaglandins (PGs) play key roles in development and maintenance of homeostasis of the adult body. Despite these important roles, it remains unclear whether the PG pathway is a target for endocrine disruption. However, several known endocrine-disrupting compounds (EDCs) share a high degree of structural similarity with mild analgesics.
Original languageEnglish
JournalEnvironmental Health Perspectives
Issue number4
Pages (from-to)534-41
Number of pages8
Publication statusPublished - 1 Apr 2011


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