Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy

Jeppe T Friborg; Ruth F Jarrett; Anders Koch; Peter Garred; June M L Freeland; Andreas Andersen; Mads Melbye

doi:10.1128/CVI.00527-09

Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy

Jeppe T Friborg, Ruth F Jarrett, Anders Koch, Peter Garred, June M L Freeland, Andreas Andersen, Mads Melbye

Department of Clinical Immunology

17 Citations (Scopus)

Abstract

In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

Original language	English
Journal	Clinical and Vaccine Immunology (Online)
Volume	17
Issue number	9
Pages (from-to)	1484-7
Number of pages	4
ISSN	1556-679X
DOIs	https://doi.org/10.1128/CVI.00527-09
Publication status	Published - 1 Sept 2010

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title = "Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy",

abstract = "In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.",

author = "Friborg, \{Jeppe T\} and Jarrett, \{Ruth F\} and Anders Koch and Peter Garred and Freeland, \{June M L\} and Andreas Andersen and Mads Melbye",

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T1 - Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy

AU - Friborg, Jeppe T

AU - Jarrett, Ruth F

AU - Koch, Anders

AU - Garred, Peter

AU - Freeland, June M L

AU - Andersen, Andreas

AU - Melbye, Mads

PY - 2010/9/1

Y1 - 2010/9/1

N2 - In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

AB - In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

UR - https://www.scopus.com/pages/publications/77956408134

U2 - 10.1128/CVI.00527-09

DO - 10.1128/CVI.00527-09

M3 - Journal article

C2 - 20610664

SN - 1556-679X

VL - 17

SP - 1484

EP - 1487

JO - Clinical and Vaccine Immunology (Online)

JF - Clinical and Vaccine Immunology (Online)

IS - 9

ER -

Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy

Abstract

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