Mannanbindende lektin og mortalitet hos patienter med type 2-diabetes--sekundaerpublikation

Troels Krarup Hansen; Mari-Anne Gall; Lise Tarnow; Steffen Thiel

Mannanbindende lektin og mortalitet hos patienter med type 2-diabetes--sekundaerpublikation

Translated title of the contribution: Mannose-binding lectin and mortality in patients with type 2 diabetes mellitus--secondary publication

Troels Krarup Hansen, Mari-Anne Gall, Lise Tarnow, Steffen Thiel

3 Citations (Scopus)

Abstract

We evaluated the relationship between serum mannose-binding lectin (MBL) and mortality and incident albuminuria in 326 patients with type 2 diabetes mellitus (T2DM). During 15 years of follow-up, 169 patients died. In a multivariate analysis, MBL was a significant risk factor for death from any cause and added to the predictive power of CRP. Normoalbuminuric patients with both high MBL and high C-reactive protein (CRP) levels had a significantly increased risk of developing albuminuria. We conclude that MBL alone or in combination with CRP can provide prognostic information on mortality and the development of albuminuria in T2DM

Translated title of the contribution	Mannose-binding lectin and mortality in patients with type 2 diabetes mellitus--secondary publication
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	171
Issue number	6
Pages (from-to)	426-9
Number of pages	4
ISSN	0041-5782
Publication status	Published - 2 Feb 2009
Externally published	Yes

Keywords

English Abstract
Journal Article

Cite this

@article{76f2348c682d419e84277347e061936e,

title = "Mannanbindende lektin og mortalitet hos patienter med type 2-diabetes--sekundaerpublikation",

abstract = "We evaluated the relationship between serum mannose-binding lectin (MBL) and mortality and incident albuminuria in 326 patients with type 2 diabetes mellitus (T2DM). During 15 years of follow-up, 169 patients died. In a multivariate analysis, MBL was a significant risk factor for death from any cause and added to the predictive power of CRP. Normoalbuminuric patients with both high MBL and high C-reactive protein (CRP) levels had a significantly increased risk of developing albuminuria. We conclude that MBL alone or in combination with CRP can provide prognostic information on mortality and the development of albuminuria in T2DM",

keywords = "Albuminuria, C-Reactive Protein, Cohort Studies, Diabetes Mellitus, Type 2, Female, Follow-Up Studies, Humans, Male, Mannose-Binding Lectin, Middle Aged, Prognosis, Proportional Hazards Models, Prospective Studies, Risk Factors, English Abstract, Journal Article",

author = "Hansen, \{Troels Krarup\} and Mari-Anne Gall and Lise Tarnow and Steffen Thiel",

year = "2009",

month = feb,

day = "2",

language = "Dansk",

volume = "171",

pages = "426--9",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "6",

}

TY - JOUR

T1 - Mannanbindende lektin og mortalitet hos patienter med type 2-diabetes--sekundaerpublikation

AU - Hansen, Troels Krarup

AU - Gall, Mari-Anne

AU - Tarnow, Lise

AU - Thiel, Steffen

PY - 2009/2/2

Y1 - 2009/2/2

N2 - We evaluated the relationship between serum mannose-binding lectin (MBL) and mortality and incident albuminuria in 326 patients with type 2 diabetes mellitus (T2DM). During 15 years of follow-up, 169 patients died. In a multivariate analysis, MBL was a significant risk factor for death from any cause and added to the predictive power of CRP. Normoalbuminuric patients with both high MBL and high C-reactive protein (CRP) levels had a significantly increased risk of developing albuminuria. We conclude that MBL alone or in combination with CRP can provide prognostic information on mortality and the development of albuminuria in T2DM

AB - We evaluated the relationship between serum mannose-binding lectin (MBL) and mortality and incident albuminuria in 326 patients with type 2 diabetes mellitus (T2DM). During 15 years of follow-up, 169 patients died. In a multivariate analysis, MBL was a significant risk factor for death from any cause and added to the predictive power of CRP. Normoalbuminuric patients with both high MBL and high C-reactive protein (CRP) levels had a significantly increased risk of developing albuminuria. We conclude that MBL alone or in combination with CRP can provide prognostic information on mortality and the development of albuminuria in T2DM

KW - Albuminuria

KW - C-Reactive Protein

KW - Cohort Studies

KW - Diabetes Mellitus, Type 2

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Mannose-Binding Lectin

KW - Middle Aged

KW - Prognosis

KW - Proportional Hazards Models

KW - Prospective Studies

KW - Risk Factors

KW - English Abstract

KW - Journal Article

UR - https://www.scopus.com/pages/publications/59849115211

M3 - Tidsskriftartikel

C2 - 19213151

SN - 0041-5782

VL - 171

SP - 426

EP - 429

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 6

ER -

Mannanbindende lektin og mortalitet hos patienter med type 2-diabetes--sekundaerpublikation

Abstract

Keywords

Other files and links

Fingerprint

Cite this