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Manglende evidens for skadelig effekt på knogleheling ved behandling med NSAID

Translated title of the contribution: No evidence of malicious effect of NSAID treatment on bone healing
  • Susanne Janum
  • , Billy Bjarne Kristensen
1 Citation (Scopus)

Abstract

The use of NSAIDs for postoperative pain management following orthopaedic surgery or during conservative treatment of fractures is controversial. Experimental animal models suggest NSAIDs inhibit bone healing. In a review of the literature, there was no clinical evidence to support categorical discard of NSAID for postoperative pain relief in uncomplicated cases. However, NSAID should be considered a potentiel risk factor of impaired bone healing and avoided in patients with a high risk of pseudoarthrosis. Recommended daily doses should be respected and duration of treatment should be limited.
Translated title of the contributionNo evidence of malicious effect of NSAID treatment on bone healing
Original languageDanish
JournalUgeskrift for Laeger
Volume174
Issue number48
Pages (from-to)3007-10
Number of pages4
ISSN0041-5782
Publication statusPublished - 2012

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