Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Manglende effekt af substitutionsbehandling ved alfa 1-antitrypsin-mangel

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Telemedicin til monitorering af inflammatoriske tarmsygdomme og colon irritabile

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Amyloid transthyretinkardiomyopati

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Rygning i graviditeten

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Androgent insensitivitetssyndrom opdaget pga. diskordans mellem prænatale vurderinger af fosterkøn.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Behandling af tymom og thymuskarcinom

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Advance care planning for patients and their relatives

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. In Vivo Selection of a Unique Tandem Repeat Mediated Azole Resistance Mechanism (TR120) in Aspergillus fumigatus cyp51A, Denmark

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Passiv rygning er en risikofaktor for udvikling af nedsat lungefunktion og KOL

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Predictors of COPD in symptomatic smokers and ex-smokers seen in primary care

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
Persons with alpha1-antitrypsin (A1AT) deficiency and chronic obstructive pulmonary disease (COPD) have been tested for the clinical value of regular intravenous infusion with A1AT in two small double-blind randomised controlled trials. The trials found a statistical significant reduction in the decrease of lung density measured by computed tomographies, but found no clinical nor statistical significant difference in respiratory symptoms, quality of life, lung function, use of medication, exacerbations, respiratory infections or survival. Based on the present evidence A1AT substitution therapy cannot be recommended.
Translated title of the contributionLack of effect of substitution therapy of alpha1-antitrypsin deficiency
Original languageDanish
JournalUgeskrift for Laeger
Volume173
Issue number42
Pages (from-to)2645-7
Number of pages3
ISSN0041-5782
Publication statusPublished - 2011

ID: 34692195