Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Is earlier better when it comes giving caffeine to preterm infants or are we risking unnecessary treatment and serious harm?

    Research output: Contribution to journalEditorialResearchpeer-review

  2. Predicting respiratory distress syndrome at birth using a fast test based on spectroscopy of gastric aspirates. 2. Clinical part

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Predicting respiratory distress syndrome at birth using fast test based on spectroscopy of gastric aspirates. 1. Biochemical part

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Undocumented migrant children in Denmark present with diverse health needs and sometimes have critical health conditions

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Measurement of peripheral arterial tonometry in patients with diabetic foot ulcers during courses of hyperbaric oxygen treatment

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. A Polygenic Risk Score Suggests Shared Genetic Architecture of Voice Break With Early Markers of Pubertal Onset in Boys

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. The External Genitalia Score (EGS): A European multicenter validation study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

AIM: The aim was to assess the influence of dietary counselling on the pubertal development and hormonal status in healthy adolescents.

METHODS: We used a subcohort of 193 healthy boys (52%) and girls (48%) from the Special Turku Coronary Risk Factor Intervention Project. Participants were recruited by nurses at the well-baby clinics in Turku Finland in 1990-1992 and randomised into intervention and control groups. Intervention children received low-saturated fat and low-cholesterol dietary counselling initiated at seven months of age. Participants were examined once a year with Tanner staging, anthropometric measurements and serial reproductive hormones from 10 to 19 years of age. In girls, postmenarcheal hormones were not analysed.

RESULTS: Pubertal hormones in boys or girls did not differ between the intervention and control groups. However, we observed slight differences in pubertal progression by Tanner staging and in anthropometric parameters. The intervention boys progressed faster to G4 (p = 0.008), G5 (p = 0.008) and P5 (p = 0.03). The intervention boys were taller than control boys (p = 0.04), while weight and body mass index did not differ.

CONCLUSION: Dietary intervention did not affect pubertal hormonal status. This finding supports the safety of implemented counselling in respect to puberty.

Original languageEnglish
JournalActa paediatrica
Volume108
Issue number2
Pages (from-to)321-327
Number of pages7
ISSN1651-2227
DOIs
Publication statusPublished - 1 Feb 2019

    Research areas

  • Dietary counselling, Low-cholesterol diet, Low-saturated-fat diet, Puberty, Sex hormones

ID: 56304105