Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

Lower Risk of Recurrence After Mesh Repair Versus Non-Mesh Sutured Repair in Open Umbilical Hernia Repair: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Type V Collagen is Persistently Altered after Inguinal Hernia Repair

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The Implementation Gap in Laparoscopic Simulation Training

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Intraoperative Tumor Perforation is Associated with Decreased 5-Year Survival in Colon Cancer: A Nationwide Database Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Large Incisional Hernias Increase in Size

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Outcomes in Clinical Trials Evaluating Interventions for the Prevention and Treatment of Hepatic Encephalopathy

    Research output: Contribution to journalReviewResearchpeer-review

  3. Getting to grips with endoscopy - Learning endoscopic surgical skills induces bi-hemispheric plasticity of the grasping network

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

BACKGROUND AND AIMS:: The use of mesh repair in a small- or middle-sized umbilical hernia remains controversial, and evidence is based on only few and small heterogeneous randomized trials. The primary aim was to assess differences, if any, in recurrence (clinical and reoperation), and secondary aim was to assess differences in infections, seroma formation, hematomas, chronic pain, cosmetic result, and quality of life.

METHOD:: A systematic review (predefined search strategy) and meta-analyses were conducted based on pre-study strict and well-defined methodology. The literature search was completed on 1 January 2018. The study protocol was registered in PROSPERO.

RESULTS:: Five randomized controlled trials were identified (mesh repair, n = 326 versus non-mesh sutured repair, n = 330) and 602 records were excluded. Randomized controlled trials included patients with defect diameters of ⩾1 to 4 cm. Mesh repair reduced the risk of recurrence compared with sutured repair with a relative risk of 0.28 (95% confidence interval = 0.13-0.58, I2 = 0%, number needed to treat = 13 patients). Additional analyses found no differences between the two surgical techniques regarding infection (relative risk = 0.80, 95% confidence interval = 0.36-1.79), seroma formation (relative risk = 1.38, 95% confidence interval = 0.57-3.32), or hematomas (relative risk = 0.55, 95% confidence interval = 0.23-1.30). Lack of sufficient data precluded meta-analysis evaluating risk of seroma formation, hematomas, chronic pain, cosmetic result, and quality of life.

CONCLUSION:: Mesh repair is recommended for umbilical hernia of ⩾1 to 4 cm. More evidence is needed for the optimal placement of the mesh (sublay or onlay) and the role of mesh in patients with an umbilical hernia <1 cm.

Original languageEnglish
JournalScandinavian Journal of Surgery
Pages (from-to)1457496918812208
ISSN1457-4969
DOIs
Publication statusE-pub ahead of print - 29 Nov 2018

ID: 55749670