Low Prevalence of Parvovirus 4 in HIV-infected Children in Denmark

Vibeke Rosenfeldt, Päivi Norja, Ellinor Lindberg, Lise Jensen, Lea Hedman, Elina Väisänen, Xuemeng Li, Klaus Hedman, Marie-Louise von Linstow

Abstract

Parvovirus 4 (PARV4) has been associated with HIV infection in adults. We examined plasma samples from 46 HIV-infected 0-year-old to 16-year-old children for the presence of PARV4. Four children (8.7%) had detectable PARV4 IgG and 1 had IgM. The result of PARV4 polymerase chain reaction was found to be negative in all patients. PARV4 seropositivity was associated with low CD4 count but not with HIV viral load.

Original languageEnglish
JournalThe Pediatric infectious disease journal
Volume34
Issue number7
Pages (from-to)761-2
Number of pages2
ISSN0891-3668
DOIs
Publication statusPublished - Jul 2015
Externally publishedYes

Keywords

  • Adolescent
  • Antibodies, Viral/blood
  • CD4 Lymphocyte Count
  • Child
  • Child, Preschool
  • Cohort Studies
  • Coinfection/epidemiology
  • Denmark/epidemiology
  • Female
  • HIV Infections/complications
  • Humans
  • Immunoglobulin G/blood
  • Immunoglobulin M/blood
  • Infant
  • Male
  • Parvoviridae Infections/epidemiology
  • Parvovirus/classification
  • Seroepidemiologic Studies

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