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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Loperamid misbrugt for at opnå euforiserende effekt hos en ung kvinde

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Loperamide is an over-the-counter anti-diarrhoeal agent. In supratherapeutic doses, loperamide penetrates the blood-brain barrier, exceeds the efflux capacity of P-glycoprotein and binds to central opioid receptors. We report a case of a 33-year-old woman with a history of opioid abuse, who had a long-term excessive daily intake of loperamide in order to achieve a euphoric effect. Cardiac arrhythmias, respiratory depression and death have been reported in relation to excessive loperamide use.

Translated title of the contributionA young woman's loperamide abuse for the achievement of euphoric effect
Original languageDanish
JournalUgeskrift for Laeger
Volume182
Issue number12
ISSN0041-5782
Publication statusPublished - 16 Mar 2020

ID: 59855898