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Long-term outcomes after out-of-hospital cardiac arrest in relation to socioeconomic status

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@article{57c5781239664952a93dc97158e970d4,
title = "Long-term outcomes after out-of-hospital cardiac arrest in relation to socioeconomic status",
abstract = "AIMS: This study aimed to examine whether socioeconomic differences exist in long-term outcomes after out-of-hospital cardiac arrest (OHCA).METHODS: We included 2,309 30-day OHCA survivors ≥30 years of age from the Danish Cardiac Arrest Registry, 2001-2014, divided in tertiles of household income (low, medium, high). Absolute probabilities were estimated using logistic regression for 1-year outcomes and cause-specific Cox regression for 5-year outcomes. Differences between income-groups were standardized with respect to age, sex, education and comorbidities.RESULTS: High-income compared to low-income patients had highest 1-year (96.4% vs. 84.2%) and 5-year (87.6% vs. 64.1%) survival, and lowest 1-year (11.3% vs. 7.4%) and 5-year (13.7% vs. 8.6%) risk of anoxic brain damage/nursing home admission. The corresponding standardized probability differences were 8.2% (95%CI 4.7-11.6%) and 13.9% (95%CI 8.2-19.7%) for 1- and 5-year survival, respectively; and -4.5% (95%CI -8.2 to -1.2%) and -5.1% (95%CI -9.3 to -0.9%) for 1- and 5-year risk of anoxic brain damage/nursing home admission, respectively. Among 831 patients <66 years working prior to OHCA, 72.1% returned to work within 1 year and 80.8% within 5 years. High-income compared to low-income patients had the highest chance of 1-year (76.4% vs. 58.8%) and 5-year (85.3% vs. 70.6%) return to work with the corresponding absolute probability difference of 18.0% (95%CI 3.8-32.7%) for 1-year and 9.4% (95%CI -3.4-22.3%) for 5-year.CONCLUSION: Patients of high socioeconomic status had higher probability of long-term survival and return to work, and lower risk of anoxic brain damage/nursing home admission after OHCA compared to patients of low socioeconomic status.",
keywords = "Long-term outcomes, Nursing home, OHCA, Return to work, Socioeconomic factors, Survival",
author = "Sidsel M{\o}ller and Mads Wissenberg and Kathrine S{\o}ndergaard and Kristian Kragholm and Fredrik Folke and {Malta Hansen}, Carolina and Ringgren, {Kristian B} and Julie Andersen and Freddy Lippert and {Lykkemark M{\o}ller}, Amalie and Lars K{\o}ber and {Alexander Gerds}, Thomas and Christian Torp-Pedersen",
note = "Copyright {\textcopyright} 2021. Published by Elsevier B.V.",
year = "2021",
month = oct,
doi = "10.1016/j.resuscitation.2021.07.015",
language = "English",
volume = "167",
pages = "336--344",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Long-term outcomes after out-of-hospital cardiac arrest in relation to socioeconomic status

AU - Møller, Sidsel

AU - Wissenberg, Mads

AU - Søndergaard, Kathrine

AU - Kragholm, Kristian

AU - Folke, Fredrik

AU - Malta Hansen, Carolina

AU - Ringgren, Kristian B

AU - Andersen, Julie

AU - Lippert, Freddy

AU - Lykkemark Møller, Amalie

AU - Køber, Lars

AU - Alexander Gerds, Thomas

AU - Torp-Pedersen, Christian

N1 - Copyright © 2021. Published by Elsevier B.V.

PY - 2021/10

Y1 - 2021/10

N2 - AIMS: This study aimed to examine whether socioeconomic differences exist in long-term outcomes after out-of-hospital cardiac arrest (OHCA).METHODS: We included 2,309 30-day OHCA survivors ≥30 years of age from the Danish Cardiac Arrest Registry, 2001-2014, divided in tertiles of household income (low, medium, high). Absolute probabilities were estimated using logistic regression for 1-year outcomes and cause-specific Cox regression for 5-year outcomes. Differences between income-groups were standardized with respect to age, sex, education and comorbidities.RESULTS: High-income compared to low-income patients had highest 1-year (96.4% vs. 84.2%) and 5-year (87.6% vs. 64.1%) survival, and lowest 1-year (11.3% vs. 7.4%) and 5-year (13.7% vs. 8.6%) risk of anoxic brain damage/nursing home admission. The corresponding standardized probability differences were 8.2% (95%CI 4.7-11.6%) and 13.9% (95%CI 8.2-19.7%) for 1- and 5-year survival, respectively; and -4.5% (95%CI -8.2 to -1.2%) and -5.1% (95%CI -9.3 to -0.9%) for 1- and 5-year risk of anoxic brain damage/nursing home admission, respectively. Among 831 patients <66 years working prior to OHCA, 72.1% returned to work within 1 year and 80.8% within 5 years. High-income compared to low-income patients had the highest chance of 1-year (76.4% vs. 58.8%) and 5-year (85.3% vs. 70.6%) return to work with the corresponding absolute probability difference of 18.0% (95%CI 3.8-32.7%) for 1-year and 9.4% (95%CI -3.4-22.3%) for 5-year.CONCLUSION: Patients of high socioeconomic status had higher probability of long-term survival and return to work, and lower risk of anoxic brain damage/nursing home admission after OHCA compared to patients of low socioeconomic status.

AB - AIMS: This study aimed to examine whether socioeconomic differences exist in long-term outcomes after out-of-hospital cardiac arrest (OHCA).METHODS: We included 2,309 30-day OHCA survivors ≥30 years of age from the Danish Cardiac Arrest Registry, 2001-2014, divided in tertiles of household income (low, medium, high). Absolute probabilities were estimated using logistic regression for 1-year outcomes and cause-specific Cox regression for 5-year outcomes. Differences between income-groups were standardized with respect to age, sex, education and comorbidities.RESULTS: High-income compared to low-income patients had highest 1-year (96.4% vs. 84.2%) and 5-year (87.6% vs. 64.1%) survival, and lowest 1-year (11.3% vs. 7.4%) and 5-year (13.7% vs. 8.6%) risk of anoxic brain damage/nursing home admission. The corresponding standardized probability differences were 8.2% (95%CI 4.7-11.6%) and 13.9% (95%CI 8.2-19.7%) for 1- and 5-year survival, respectively; and -4.5% (95%CI -8.2 to -1.2%) and -5.1% (95%CI -9.3 to -0.9%) for 1- and 5-year risk of anoxic brain damage/nursing home admission, respectively. Among 831 patients <66 years working prior to OHCA, 72.1% returned to work within 1 year and 80.8% within 5 years. High-income compared to low-income patients had the highest chance of 1-year (76.4% vs. 58.8%) and 5-year (85.3% vs. 70.6%) return to work with the corresponding absolute probability difference of 18.0% (95%CI 3.8-32.7%) for 1-year and 9.4% (95%CI -3.4-22.3%) for 5-year.CONCLUSION: Patients of high socioeconomic status had higher probability of long-term survival and return to work, and lower risk of anoxic brain damage/nursing home admission after OHCA compared to patients of low socioeconomic status.

KW - Long-term outcomes

KW - Nursing home

KW - OHCA

KW - Return to work

KW - Socioeconomic factors

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=85113303048&partnerID=8YFLogxK

U2 - 10.1016/j.resuscitation.2021.07.015

DO - 10.1016/j.resuscitation.2021.07.015

M3 - Journal article

C2 - 34302925

VL - 167

SP - 336

EP - 344

JO - Resuscitation

JF - Resuscitation

SN - 0300-9572

ER -

ID: 67035504