Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Long-term motor skill training with individually adjusted progressive difficulty enhances learning and promotes corticospinal plasticity

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Simvastatin improves mitochondrial respiration in peripheral blood cells

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Discrete finger sequences are widely represented in human striatum

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Author Correction: Assessment of brain reference genes for RT-qPCR studies in neurodegenerative diseases

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Guidelines for TMS/tES Clinical Services and Research through the COVID-19 Pandemic

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Acute exercise protects newly formed motor memories against rTMS-induced interference targeting primary motor cortex

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Direct exposure of the head to solar heat radiation impairs motor-cognitive performance

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Lasse Christiansen
  • Malte Nejst Larsen
  • Mads Just Madsen
  • Michael James Grey
  • Jens Bo Nielsen
  • Jesper Lundbye-Jensen
View graph of relations

Motor skill acquisition depends on central nervous plasticity. However, behavioural determinants leading to long lasting corticospinal plasticity and motor expertise remain unexplored. Here we investigate behavioural and electrophysiological effects of individually tailored progressive practice during long-term motor skill training. Two groups of participants practiced a visuomotor task requiring precise control of the right digiti minimi for 6 weeks. One group trained with constant task difficulty, while the other group trained with progressively increasing task difficulty, i.e. continuously adjusted to their individual skill level. Compared to constant practice, progressive practice resulted in a two-fold greater performance at an advanced task level and associated increases in corticospinal excitability. Differences were maintained 8 days later, whereas both groups demonstrated equal retention 14 months later. We demonstrate that progressive practice enhances motor skill learning and promotes corticospinal plasticity. These findings underline the importance of continuously challenging patients and athletes to promote neural plasticity, skilled performance, and recovery.

Original languageEnglish
JournalScientific Reports
Volume10
Issue number1
Pages (from-to)15588
ISSN2045-2322
DOIs
Publication statusPublished - 24 Sep 2020

ID: 60934806