Longitudinal Immune Profiling of T Cell Exhaustion During IL-17A Blockade in a Patient With HLA-B27-negative Spondyloarthritis and Sjögren’s Syndrome: A Case Report

Keyphrases

• Interleukin-17 (IL-17) 100%
• Spondyloarthritis 100%
• Immune Profiling 100%
• Human Leukocyte antigen-B27 100%
• T Cell Exhaustion 100%
• C-reactive Protein 50%
• Ankylosing Spondylitis 50%
• Secukinumab 50%
• Stevens-Johnson Syndrome 50%
• Tumor Necrosis Factor Inhibitor (TNFi) 50%
• Programmed Cell Death Protein 1 (PD-1) 50%
• Flow Cytometry 25%
• Disease Activity 25%
• Remission 25%
• Rate-2 25%
• Nave 25%
• Non-steroidal Anti-inflammatory Drugs (NSAIDs) 25%
• Clinical Improvement 25%
• Autoimmune 25%
• Older Men 25%
• T Cells 25%
• Natural Killer Cells 25%
• Ankylosing Spondylitis Disease Activity Score (ASDAS) 25%
• Erythrocyte Sedimentation Rate 25%
• Low-to-moderate 25%
• Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) 25%
• Low Disease Activity 25%
• Long-term Stability 25%
• Effector T Cells 25%
• Laboratory Data 25%
• Early Therapy 25%
• Moderate Disease Activity 25%
• Lectin-like 25%
• Regulatory T Cell(Treg) 25%
• Serial Monitoring 25%
• Immunoglobulin Domain 25%
• Autoimmune Syndrome 25%
• T Cell Regulation 25%
• Year 2020 25%
• Immune Exhaustion 25%
• T Cell Immunoglobulin 25%
• Regulatory Dynamics 25%
• Fas Cell Surface Death Receptor 25%
• Personalized Management 25%
• Steroid Tapering 25%
• Immune Regulatory 25%
• Mucin-like Domain 25%
• Immune Adaptation 25%

Medicine and Dentistry

• Human Leukocyte Antigen 100%
• Spondylarthritis 100%
• Interleukin 17 100%
• T Cell Exhaustion 100%
• Disease Activity 75%
• T Cell 75%
• C Reactive Protein 50%
• Ankylosing Spondylitis 50%
• Autoimmunity 50%
• Programmed Death 1 Receptor 50%
• Stevens-Johnson Syndrome 50%
• Secukinumab 50%
• Tumor Necrosis Factor 25%
• Flow Cytometry 25%
• Nonsteroid Antiinflammatory Agent 25%
• TNF Inhibitor 25%
• Regulatory T Cell 25%
• Immunoglobulin 25%
• Cell Surface 25%
• BASDAI 25%
• Mucin 25%
• Ankylosing Spondylitis Disease Activity Score 25%
• Death Receptor 25%
• Steroid Therapy 25%
• Erythrocyte Sedimentation Rate 25%
• Natural Killer Cell Lectin Like Receptor 25%
• Steroid 25%

Immunology and Microbiology

• Human Leukocyte Antigen 100%
• Ankylosing Spondylitis 100%
• Interleukin 17 100%
• T Cell Exhaustion 100%
• Spondylarthritis 100%
• T Cell 75%
• C-Reactive Protein 50%
• Autoimmunity 50%
• Regulatory T Cell 50%
• Secukinumab 50%
• Programmed Death 1 Receptor 50%
• Stevens Johnson Syndrome 50%
• Steroid 50%
• Intravenous Immunoglobulin 25%
• Cell Surface 25%
• Tumor Necrosis Factor 25%
• TNF Inhibitor 25%
• Killer Cell 25%
• Lectin 25%
• Mucin 25%
• Death Receptor 25%
• Erythrocyte Sedimentation Rate 25%